🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Yesterday, I nailed my first book to a wall. Thanks for everyone stopping by and cheering for that moment! You can now come to Flemingsberg and read it at the library OR you follow this link and read my thesis wherever you want: doi.org/10.69622/27119…

Happy to share our latest work by Yexin Yang et al. on antibody-mediated control of endogenous retroviruses in mice. In the process, we found “natural antibodies” with broad reactivity against enveloped viruses. Here is how “panviral” antibodies work 🧵(1/) science.org/doi/10.1126/sc…

Counting down the days to my PhD defense in a week, here is a small interview on the projects that I worked on for the past 4-ish years! news.ki.se/new-thesis-on-…

Today, I’m sharing another insanely good o1-Pro scientific insight! This one is particularly special to me to a point of making me emotional, its that profound🥹 I asked o1-Pro to critically evaluate a review my students & I had written about a specific subset of immune cells

Just in time for the new year: scRepertoire 2: Enhanced and Efficient Toolkit for Single-Cell Immune Profiling biorxiv.org/content/10.110…

Pseudobulk VDJ feature space used to estimate pseudotime in T cell development. Cool vignette for DandelionR with scRepertoire. tuonglab.github.io/dandelionR/art…

Latest paper from lab, where Awad et al describe how cigarette smoke impacts that MAIT-MR1 axis and implications for lung diseases. In collaboration with Fairlie, Hansbro and Corbett labs doi.org/10.1084/jem.20… Monash Biomedicine Discovery Institute NHMRC Wael Awad Monash University Prof. Jamie Rossjohn Journal of Experimental Medicine

I need people to understand how difficult it is to get an NIH grant. You spend months writing a proposal, following strict guidelines that include a detailed multiyear budget, bios of everyone on your team, plans for participant safety & ethical conduct. Then you send it off -1/n

Granzyme K activates the entire complement cascade nature.com/articles/s4158… nature Erin Theisen, MD, PhD A. Helena Jonsson

Arif Arif please try the link below, it should be free access medium.com/@nikolay-oskol…

Feature selection methods affect the performance of scRNA-seq data integration and querying❤️ nature.com/articles/s4159…

Bioinformatics Tip: Why Wet Biologists Should Involve Bioinformaticians Early in Experiment Design 🧵

What if TCRs didn’t need to see peptides to bind MHC? A newly identified human TCR docks sideways onto HLA-DQ2.5—like an antibody. This could reshape how we think about antigen recognition 🧐🧐 Monash University Monash Medicine, Nursing and Health Sciences Rossjohn lab Nature Communications Congrats!

Triggered by the microbiota, gut-resident CD8+ T cells release IFNγ to preserve organ function and host mortality through stromal cell-specific signaling and recruitment of tissue-protective neutrophils cell.com/cell/fulltext/… Cell Irah King Susan Westfall

From Transcripts to Cells: Dissecting Sensitivity, Signal Contamination, and Specificity in Xenium Spatial Transcriptomics biorxiv.org/content/10.110…

Our work co-led by Scripps Research Graduate Program students Dominic Haas & Jonathan Melamed shows that microbial tropism determines how metabolites are presented to #MAIT cells. Thanks to NIH, U.S. National Science Foundation, & NSERC / CRSNG, & Scripps Research for supporting our research!

Popular methods like UMAP & t-SNE are stochastic and distort data structure. Bonsai - a novel method - builds trees to relate high-dimensional objects, accounting for measurement noise. biorxiv.org/content/10.110…

Our third webinar from the AUS/APAC region, will feature Nick Gherardin and Sho Yamasaki. Thursday, June 12th at 17:00 AEST (8:00 London, 16:00 Tokyo). If you'd like to keep up to date, sign up to the mailing list here: cd1mr1.com/cd1-mr1-society

When another scientist gives you a tour of their lab they're always like "here's the regular equipment I know you've seen it a million times so boring" but I genuinely love land snorkeling through other people's labs and noticing tiny details about how they organize things

🚀 Xaira Therapeutics has just dropped a game-changer for AI-driven biology. Today, we unveiled X-Atlas/Orion, the largest publicly available genome-wide Perturb-seq dataset to date—spanning 8.4 million single cells with perturbations across all ~20,000 human protein-coding