Thomas Pierret 🫁 (@tomprt) 's Twitter Profile
Thomas Pierret 🫁

@tomprt

#MD #pulmonologist #lungcancer

ID: 493917426

calendar_today16-02-2012 10:06:18

4,4K Tweet

363 Followers

762 Following

Hidehito HORINOUCHI (@hhorinouchi) 's Twitter Profile Photo

🆕 #ASCO25 🆙 ☑️#LCSM Poster 🔥Dynamic changes in target protein exp. following Tx in NSCLC: Simultaneous evaluation of MET, TROP2, HER2, B7-H4, and MDM2 in paired biopsies 🎙️ Dr. Saori Murata Hidehito HORINOUCHI 📌Poster Bd71, Abstr 8591 OncoAlert ASCO meetings.asco.org/2025-asco-annu…

🆕 #ASCO25 🆙
☑️#LCSM Poster
🔥Dynamic changes in target protein exp. following Tx in NSCLC: Simultaneous evaluation of MET, TROP2, HER2, B7-H4, and MDM2 in paired biopsies
🎙️ Dr. Saori Murata <a href="/HHorinouchi/">Hidehito HORINOUCHI</a>
📌Poster Bd71, Abstr 8591
<a href="/OncoAlert/">OncoAlert</a> <a href="/ASCO/">ASCO</a>
meetings.asco.org/2025-asco-annu…
Sanjay Popat (@drsanjaypopat) 's Twitter Profile Photo

NeoADAURA, Osi/osi-chemo/chemo neoadj 2 vs 8% PD rate MPR 26 vs 25 vs 2%: benefit across genotype & stage. Greater depth response by osi-chemo>osi Nodal downstaging in both osi arms Osi/osi-chemo reduces PD, gets MPR Impressive EFS by MPR vs not #ASCO25

NeoADAURA,
Osi/osi-chemo/chemo neoadj 
2 vs 8% PD rate 
MPR 26 vs 25 vs 2%: benefit across genotype &amp; stage. Greater depth response by osi-chemo&gt;osi
Nodal downstaging in both osi arms 
Osi/osi-chemo reduces PD, gets MPR

Impressive EFS by MPR vs not 

#ASCO25
Lola Lozano (@mdlozanoe) 's Twitter Profile Photo

Key diagnostic cytological features of lung small cell carcinoma: -Chromatine: fine & dark - Nucleoli: absent or inconspicuous -Cytoplasm: scant Bonuns: nuclear molding, crush artifact, apoptotic cells, blue bodies, necrosis, 🔬💯🫁 👇

Key diagnostic cytological features of lung small cell carcinoma:
-Chromatine: fine &amp; dark 
- Nucleoli: absent or inconspicuous
-Cytoplasm: scant 
Bonuns: nuclear molding, crush artifact, apoptotic cells, blue bodies, necrosis, 🔬💯🫁 👇
ERS publications (@erspublications) 's Twitter Profile Photo

ERJ Open Research: Variants of SFTPA1 and SFTPA2 are involved in interstitial lung disease and lung cancer. Penetrance for the first event is 50% at 60 years old, rising to 89.3% at 80. Penetrance for lung cancer reached 50% at age 80, earliest case diagnosed at age 30.

ERJ Open Research: Variants of SFTPA1 and SFTPA2 are involved in interstitial lung disease and lung cancer. Penetrance for the first event is 50% at 60 years old, rising to 89.3% at 80. Penetrance for lung cancer reached 50% at age 80, earliest case diagnosed at age 30.
Lung Cancer Europe (@lungcancereu) 's Twitter Profile Photo

#Lungcancer in never-smokers is rising but Europe’s screening policies still focus almost entirely on age & smoking history. That’s leaving thousands invisible to early detection. bbc.com/future/article… We need screening policies that reflect real-world risk, not just smoking

Annals of Oncology (@annals_oncology) 's Twitter Profile Photo

🆕article in press: DNA methyltransferase 3A (DNMT3A) mutations and PD-(L)1 blockade efficacy in non-small cell lung cancer annalsofoncology.org/article/S0923-… Mark Awad Biagio Ricciuti, MD, PhD

🆕article in press: DNA methyltransferase 3A (DNMT3A) mutations and PD-(L)1 blockade efficacy in non-small cell lung cancer annalsofoncology.org/article/S0923-… <a href="/DrMarkAwad/">Mark Awad</a> <a href="/BRicciutiMD/">Biagio Ricciuti, MD, PhD</a>
Stephen V Liu, MD (@stephenvliu) 's Twitter Profile Photo

FDA grants breakthrough designation to YL201 for #SCLC. YL201 is a B7-H3 directed ADC with a proprietary topoisomerase-1 inhibitor payload. Looking forward to more data from the ongoing trials. medilinkthera.com/news-details/48

FDA grants breakthrough designation to YL201 for #SCLC. YL201 is a B7-H3 directed ADC with a proprietary topoisomerase-1 inhibitor payload. Looking forward to more data from the ongoing trials.

medilinkthera.com/news-details/48
Laurent Greillier (@lgreillier) 's Twitter Profile Photo

Merci Fabrice Barlesi pour ta très belle conférence sur les mécanismes de résistance à l’immunothérapie au cours de la réunion plénière du GFPC à Marseille ! Pascale Tomasini

Merci <a href="/barlesi/">Fabrice Barlesi</a>  pour ta très belle conférence sur les mécanismes de résistance à l’immunothérapie au cours de la réunion plénière du GFPC à Marseille ! <a href="/PascaleTomasini/">Pascale Tomasini</a>
Jennifer A. Marks, MD (@jennifermarksmd) 's Twitter Profile Photo

Dr. Anjali Rohtagi discusses the ongoing trial utilizing sacituzumab govitecan in advanced thymoma and thymic carcinoma at Georgetown University and Stanford Medicine under PI Dr. Chul Kim . Shout out to Dr. Heather Wakelee as site PI. #DAVALung #HawaiiiLung25 #thymsm ITMIG Society

Dr. Anjali Rohtagi discusses the ongoing trial utilizing sacituzumab govitecan in advanced thymoma and thymic carcinoma at <a href="/Georgetown/">Georgetown University</a> and <a href="/StanfordMed/">Stanford Medicine</a> under PI Dr. <a href="/chulkimMD/">Chul Kim</a> . Shout out to Dr. <a href="/HwakeleeMD/">Heather Wakelee</a> as site PI.
#DAVALung #HawaiiiLung25 #thymsm <a href="/Itmig_society/">ITMIG Society</a>
Jennifer A. Marks, MD (@jennifermarksmd) 's Twitter Profile Photo

Dr. Chul Kim highlights 1L carbo+pac+rami in thymic carcinoma as the new standard of care. While some data for use of chemoIO upfront, high rates here of immune related adverse events! Heather Wakelee #DAVALung #HawaiiiLung25 #thymsm ITMIG Society

Dr. <a href="/chulkimMD/">Chul Kim</a> highlights 1L carbo+pac+rami in thymic carcinoma as the new standard of care. While some data for use of chemoIO upfront, high rates here of immune related adverse events!  <a href="/HwakeleeMD/">Heather Wakelee</a> 
#DAVALung #HawaiiiLung25 #thymsm <a href="/Itmig_society/">ITMIG Society</a>
Dr. Estela Rodriguez (@latinamd) 's Twitter Profile Photo

Je ne sais pas 🤷🏽‍♀️but I don’t find this doubling in #lungcancer overall survival from 8.5 mos to 20.7 mos in the last 20 yrs in 🇫🇷 still enough progress to celebrate. ➡️However, it highlights that effective systemic targeted therapy and immunotherapy can move the needle for

Je ne sais pas 🤷🏽‍♀️but I don’t find this doubling in #lungcancer overall survival from 8.5 mos to 20.7 mos in the last 20 yrs in 🇫🇷 still enough progress to celebrate. 

➡️However, it highlights that effective systemic targeted therapy and immunotherapy can move the needle for
Al-Ola A Abdallah MD (USMIRC) (@abdallah81md) 's Twitter Profile Photo

2/📉 CRS incidence dropped to 10% with a single pre-step-up dose of tocilizumab (8 mg/kg). ✅ 10 of 12 CRS cases were Grade 1 ❌ No Grade ≥3 CRS ❌ No repeat tocilizumab or steroid needed ➡️ Compared to ~36–58% CRS in registrational trials, this is remarkable. #mmsm #MedEd

2/📉 CRS incidence dropped to 10% with a single pre-step-up dose of tocilizumab (8 mg/kg).
✅ 10 of 12 CRS cases were Grade 1
❌ No Grade ≥3 CRS
❌ No repeat tocilizumab or steroid needed
➡️ Compared to ~36–58% CRS in registrational trials, this is remarkable.

#mmsm #MedEd
Jarushka Naidoo (@drjnaidoo) 's Twitter Profile Photo

💡Starting out in thoracic oncology? The IASLC Communications Committee proudly brings you: ‘50 Years of Progress in NSCLC: A New Fellow’s Guide in the Clinic’ A whistlestop tour of key advances, distilled by global leaders JTO & JTO CRR OncoAlert #LCSM jto.org/article/S1556-…

Lung Cancer Europe (@lungcancereu) 's Twitter Profile Photo

People with #lungcancer & low BMI are more likely to develop brain metastases - a link not seen in other cancers. New open access study in Nature Communications, July 2025. Researchers suggest it’s driven by brain signalling changes, not just weight loss. 🔗

People with #lungcancer &amp; low BMI are more likely to develop brain metastases - a link not seen in other cancers.

New open access study in Nature Communications, July 2025.

Researchers suggest it’s driven by brain signalling changes, not just weight loss.

🔗
Roberto Ferrara (@robertoferrara_) 's Twitter Profile Photo

❄️Winter of cancer immunotherapy is here. 𝐀𝐥𝐥-𝐜𝐨𝐦𝐞𝐫𝐬 𝐚𝐩𝐩𝐫𝐨𝐚𝐜𝐡 & 𝐍𝐞𝐭𝐰𝐨𝐫𝐤-𝐞𝐟𝐟𝐞𝐜𝐭 slowed progress-we’ve hit a plateau. Time to prioritize innovation over convention! Editorial out in JTO & JTO CRR bit.ly/4eEVcv4 Fabio Salomone Antonio Nuccio

❄️Winter of cancer immunotherapy is here. 𝐀𝐥𝐥-𝐜𝐨𝐦𝐞𝐫𝐬 𝐚𝐩𝐩𝐫𝐨𝐚𝐜𝐡 &amp; 𝐍𝐞𝐭𝐰𝐨𝐫𝐤-𝐞𝐟𝐟𝐞𝐜𝐭 slowed progress-we’ve hit a plateau. 
Time to prioritize innovation over convention!
Editorial out in <a href="/JTOonline/">JTO & JTO CRR</a> bit.ly/4eEVcv4
<a href="/FabioSalomone22/">Fabio Salomone</a> <a href="/AntonioNuccio01/">Antonio Nuccio</a>
Goutham Sunny (@medoncodoc) 's Twitter Profile Photo

🚨 Nadunolimab + Platinum Doublet Shows Promising Activity in 2L NSCLC Post-ICI 🧬💥 🔬 Study Focus: Nadunolimab, an anti-IL1RAP monoclonal antibody, was evaluated with platinum-doublet chemotherapy in advanced NSCLC (1L and 2L post-pembrolizumab) in a phase I/II study

🚨 Nadunolimab + Platinum Doublet Shows Promising Activity in 2L NSCLC Post-ICI 🧬💥

🔬 Study Focus:
Nadunolimab, an anti-IL1RAP monoclonal antibody, was evaluated with platinum-doublet chemotherapy in advanced NSCLC (1L and 2L post-pembrolizumab) in a phase I/II study
Thomas Pierret 🫁 (@tomprt) 's Twitter Profile Photo

🚨 Poste toujours disponible même sur une plus courte durée ! Pérennisation du poste possible par la suite malgré retour du congé maternité ‼️

JAMA (@jama_current) 's Twitter Profile Photo

Non-cystic fibrosis (CF) bronchiectasis is a chronic lung condition that typically causes cough and sputum production. Learn more in this Review. ja.ma/4kJZOBi

Non-cystic fibrosis (CF) bronchiectasis is a chronic lung condition that typically causes cough and sputum production. 

Learn more in this Review.

ja.ma/4kJZOBi