In our latest work we use #CryoEM to analyze polyethylene degrading proteins directly from native source🐛. Great collaboration with the groups of Federica Bertocchini (CIB Margarita Salas (CSIC)) and Maria Solà (IBMB). Brief summary below🧵👇 and full story here: science.org/doi/full/10.11…

This was a wonderful meeting! So happy to see such a healthy and productive Iberian cryo-EM community! #MFS2023 #cryoEM Many thanks to all the organizers :)

The exchange of knowledge and the strengthening of scientific and technical collaborations made the #MFS2023 at @inlnano a huge success. + inl.int/mfs2023-confer… #inl #inlnano #mfs2023 #conference #microscopy #electronmicroscopy

¡Damos la bienvenida a la nueva directora y vicedirectores! Agradecemos su labor al equipo saliente y tenemos muchas ganas de seguir trabajando de cerca estos años.

We are very excited to share the structure of the T. brucei MCC and a putative activation mechanism! Out now in structure: cell.com/structure/full…

Check it out! We had a wonderful time working on this challenging enzyme:

La publicación de #AlphaFold3 nos trae muchas oportunidades en el campo, especialmente para los que trabajamos en interacciones proteína-ácido nucleico. Carlos da unas pinceladas sobre su gran potencial, pero también sus posibles limitaciones, en ABC.es: abc.es/ciencia/carlos…

Nuestro investigador Carlos Fernández Tornero escribe en ABC.es en relación a las ventajas y limitaciones del nuevo AlphaFold 3. Puedes leerlo aquí 👇

Thrilled to share our last work Cell Reports Physical Science Revealing the molecular mechanism of an anti-tumoral compound inhibiting our favourite system, RUVBL1/2 (at 2.4 Å resolution)🔥 All-Llorca lab work led by Carmen Garcia and Andrés López Perrote Link below 👇 doi.org/10.1016/j.xcrp…

El pasado jueves estuvo Carlos en el #GoogleCloudSummitMadrid compartiendo nuestros últimos resultados, obtenidos con el apoyo de Alphafold, sobre complejos enzimáticos del parásito de la enfermedad del sueño: pubmed.ncbi.nlm.nih.gov/38593794/

We are delighted to see our review come out in Current Opinion/Research in Structural Biology, where we review recent advances in the understanding of ion-driven rotary membrane motors.  Read it here:sciencedirect.com/science/articl… CPRatUCPH (1/5)

We are happy to share our latest work on RNA polymerase I! We continued our #CryoEM study of its stalling mechanism, this time at abasic lesions, and uncovered interesting Pol I configurations. Read more at bioRxiv: biorxiv.org/content/10.110…

Have you ever heard of 11-subunit RNA polymerase I? We describe a structure lacking A12 in addition to A49/A34.5!

We're hiring! Are you looking for a PhD position in structural biology? We offer a fully-funded 4 year contract to study basic processes connected to transcription. If you're interested in joining us in sunny Madrid, get in touch with us!

📢 El servicio de microscopía electrónica del CIB Margarita Salas (CSIC) está buscando personas interesadas en solicitar un contrato #PTA2024. 📅 Fecha límite envío de expresiones de interés: 20/11/2024 Más info 👇 aei.gob.es/convocatorias/…

You can now also find us at bluesky! bsky.app/profile/torner…