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Hidden Protein Defects Behind Autism Identified Researchers developed a groundbreaking mouse stem cell library featuring 63 autism-associated gene variants. Using CRISPR and embryonic stem cell technology, the team created a powerful tool to study how specific genetic

“ES cell models of autism with copy number variations reveal cell-type-specific translational vulnerability” by TAKUMI Toru et al. Cell Genomics dx.doi.org/10.1016/j.xgen…

Dr. Toru Takumi and colleagues establish a biological resource including 63 genetically modified #mESC lines as genetic models of #autism spectrum disorder. | Cell Genomics 🔗 bit.ly/4jKkjx6

“Autism in a dish” Read the newest research news from #KobeU here: kobe-u.ac.jp/en/news/articl…

Also check out the full paper by Toru Takumi: doi.org/10.1016/j.xgen…

【注目プレスリリース】世界唯一の自閉症細胞モデルのコレクション / 神戸大学 research-er.jp/articles/view/…

ESC models of autism with copy-number variations reveal cell-type-specific translational vulnerability dlvr.it/TLKRqj

Hidden Protein Defects Behind Autism Identified - neurosciencenews.com/asd-crispr-gen… @neurosciencenewより

A library of ESC models for neuropsychiatric disorders ESC models of autism with copy-number variations reveal cell-type-spec... sciencedirect.com/science/articl…

Wow in Greek Αυτισμός: Σημαντική πρόοδος μέσω του εργαλείου CRISPR για την κατανόηση των αιτιών που τον προκαλούν techgear.gr/aytismos-siman… TechGear.grより

Autism in a dish ESC models of autism with copy-number variations reveal cell-type-specific translational vulnerability: Cell Genomics cell.com/cell-genomics/…

Shun-ichi Amari | Kyoto Prize kyotoprize.org/en/laureates/s…

Cell Bank Reveals Autism's Genetic Roots | Technology Networks technologynetworks.com/tn/news/cell-b…

Chd8 Dup model published from Dr Nishiyama Duplication of the autism-related gene Chd8 leads to behavioral hyperactivity and neurodevelopmental defects in mice | Nature Communications nature.com/articles/s4146…

These parenchymal or extra vascular T cells are what we have been searching for over the last four years. Yoshida-san, the first author, stated that she initiated the project five years ago. The subfornical organ is a nucleus for gut-derived T cells… nature.com/articles/s4158…

Human-like expression of the CLOCK gene in mouse neocortex enhances cognitive flexibility and neural connectivity, suggesting an evolutionary gain of function Yuxiang Liu Konopka Lab Joseph Takahashi nature.com/articles/s4159…

神戸大、自閉症細胞モデル作製　治療薬候補発見に期待 | 日刊工業新聞 電子版 nikkan.co.jp/articles/view/…

Inter-brain neural dynamics in biological and artificial intelligence systems | Nature nature.com/articles/s4158…

Editorial overview: Mechanisms underlying neurodevelopmental disorders sciencedirect.com/science/articl…