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Excited to share our collaborative manuscript demonstrating a circulating genetic signature in patients with symptomatic #PAD ahajournals.org/doi/10.1161/AT… @JDNewmanMDMPH Karmen Ruggles @AdrianaHeguy @NYUCVRC

A multidisciplinary team of investigators from NYU, Brigham and Women’s and Yale characterized a whole-blood transcript signature of patients with symptomatic PAD and PAD patients at increased risk of major adverse cardiac and limb events. @JDNewmanMDMPH Dr. Jeffrey Berger Karmen Ruggles

Pleased to share 18 months of work demonstrating how #platelets play a major pathogenic role in #Covid_19 and amplify endotheliopathy Tessa Barrett 👩‍🔬🧫🫀🧬🗽🇦🇺 Matthew D. Neal, MD Lucy Zumwinkle Kornblith, MD, FACS Karmen Ruggles @NYUCVRC @NHLBI_BLOODDir @nih_nhlbi Eugene Yuriditsky MacIntosh Cornwell science.org/doi/10.1126/sc…

Very excited to be a part of this project. When COVID began, everyone in medicine shifted their work to help however they could. I hope this work helps us understand and finally beat this thing.

Platelets Contribute to Disease Severity in COVID‐19 - another collaborative journey with Tessa Barrett 👩‍🔬🧫🫀🧬🗽🇦🇺 and others at NYU Grossman School of Medicine and NIH MacIntosh Cornwell Karmen Ruggles onlinelibrary.wiley.com/doi/abs/10.111…

A collaborative journey to investigate mechanisms of myocardial injury - Risk factors, transcriptomics, and outcomes of myocardial injury following lower extremity revascularization rdcu.be/cL3Ih @NSmilowitzMD Svati Shah Karmen Ruggles MacIntosh Cornwell @JDNewmanMDMPH

Dr. Rinath Jeselsohn (Rinath Jeselsohn) and colleagues published a new study examining how a "A Distinct Chromatin State Drives Therapeutic Resistance in Invasive Lobular #BreastCancer." #bcsm pubmed.ncbi.nlm.nih.gov/35950920/

Proud to present our latest work on the human lncRNA CHROMR. We show that CHROMR restricts viral replication by licensing the interferon-stimulated gene response. #COVID19 #inflammation #influenza PNASNews Kathryn Moore Lab NYU CVRC pnas.org/doi/10.1073/pn…

Great collaboration between #cardiology and #rheumatology demonstrating that #Platelets are induce myeloid inflammation in SLE #Lupus MacIntosh Cornwell Tessa Barrett 👩‍🔬🧫🫀🧬🗽🇦🇺 Karmen Ruggles onlinelibrary.wiley.com/doi/10.1002/ar…

Recent study led by @CRollingMD investigating how antiplatelet Rx’s affect mono-plt aggregate formation & their impact on monocyte inflam. processes (e.g. SOCS3) Big effort by many in the lab!! Marcin Sowa Tricia Wang MacIntosh Cornwell Tamar Schwartz Dr. Jeffrey Berger🧪 pubmed.ncbi.nlm.nih.gov/36630990/

Dr. Michael Garshick and colleagues demonstrating the pathogenic overlap of #psoriasis and #cardiovascular disease Tessa Barrett 👩‍🔬🧫🫀🧬🗽🇦🇺 MacIntosh Cornwell Brittany Weber Karmen Ruggles NYU CVD Prevention NYU Langone Health onlinelibrary.wiley.com/doi/10.1111/jd…

Thrilled to have been a part of this important collaboration at the intersection of cardiology, rheumatology, and computational biology!! Excited to see where this story will lead!

Tessa Barrett 👩‍🔬🧫🫀🧬🗽🇦🇺 has great presentation showing #platelet activity and transcriptomics can predict increased risk of acquired #bleeding ISTH #isth2023 Karmen Ruggles MacIntosh Cornwell NYU CVD Prevention

Finally! A circulating platelet genetic signature (PRESS)🔥that predicts platelet hyperreactivity and increased cardiovascular risk. Collaborative science is awesome!! Tessa Barrett 👩‍🔬🧫🫀🧬🗽🇦🇺 @NSmilowitzMD NYU CVD Prevention NYU CVRC nature.com/articles/s4146…