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Find out how genome loci are anchored to the nucleolus! Exciting preprint Trono Lab shows that ZNF274 competes with CTCF to keep H3K9me3 silenced genome at the nucleolus periphery, fine-tuning cell-specific gene expression. preLight: Sílvia Carvalho ⬇️ prelights.biologists.com/highlights/clu…

Abstract submission deadline for our #transposons meeting is 31 July! Join us in Leicester and hear from amazing speakers: Oded Rechavi Cedric🧬➰🧬Feschotte @DeborahBourchis Trono Lab Kathleen Helen Burns Pascale Lesage RoweLab Donal O'Carroll Pontus Skoglund genetics.org.uk/events/the-rea…

Excited to soon embark on a year-long sabbatical in Lausanne 🇨🇭as a visiting prof in Trono Lab EPFL! It’s only an “au revoir”, lab 💕👋

Didier Trono Lab preaching 🦀 ZFPs! I’m a convert! Our genome encodes ~400 KZFPs. Most bind to a single or a few TE subfamilies. A crucial layer of control over the ocean of cis-regulatory elements dispersed by TEs throughout the genome. #cshlTE24

Thrilled to share our findings on early aGVHD detection! Single-cell transcriptome analysis reveals atypical monocytes circulating before clinical onset. Huge thanks to Geneva Hospital’s onco-pediatric unit, CANSEARCH, and our lab. Proud of this teamwork! academic.oup.com/jleukbio/artic…

We start our afternoon session with Trono Lab talking about transposable elements, their polydactyl domesticators and the species-specificity of human biology #GSTransposons

Next week on March 6th, we welcome Wayo Matsushima as the latest guest in our Max Planck Seminar Series. Wayo is EMBO Postdoc in the Trono Lab, EPFL and we look forward to an interesting talk in which he opens up the (human) genome and its treasure trove of strange features: TEs

New preprint from the lab! More to come soon. Please follow us also on Bluesky: bsky.app/profile/trono-…