🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

💎Brilliant new work from David Rueda, MRC Laboratory of Medical Sciences (LMS) Imperial Department of Infectious Disease & Structural and Synthetic Biology in nature uncovers how the SWR1 enzyme reduces genome instability by ‘flipping’ nucleosomes over to modify histones on each side. bit.ly/3NVGZNz

NEWS - The John Innes Centre awarded major investment for doctoral students We are pleased to announce the Biotechnology and Biological Sciences Research has awarded us a Doctoral Landscape Award, in partnership with UEA The Sainsbury Laboratory Quadram Institute Earlham Institute Norwich Research Park okt.to/SwarpW

Many congratulations, Jovana!!!

The 1st rule of day science is to ask for each result, what is the negative control and what is the positive control, because we forget how easy it is to fool ourselves.

Siân Owen Michael Baym Natalia Quinones-Olvera What if we dug into a sample a little more “wild” and a little less characterized? We combined our strains with a wastewater sample (thank you Boston for your ~contributions~), and we found fluorescent hits! Each was isolated and characteristics confirmed on monoculture lawns. 5/

Brilliant idea!!!

🚨New discovery in the fight against antibiotic resistance! Together with researchers Uniwersytet Jagielloński and John Innes Centre, we have captured a new image of DNA gyrase in action using cryo-EM, enhancing our understanding of the vital bacterial enzyme. pnas.org/doi/10.1073/pn…

Our researchers together with Centre for Programmable Biological Matter Durham University and the John Innes Centre Centre have revealed groundbreaking insights into DNA gyrase. Using cryo-EM, they’ve revealed how this enzyme works, which can be used to design new antibiotics to fight resistant bacteria.💊

doi.org/10.1038/d41586… Check out our story! From inseparable undergrads in Belgrade to PhDs scattered across the globe, FFDS (Four Friends Doing Science) kept us inspiring each other, no matter the distance. Can you guess who’s who😆? Boris Stojilkovic Milica Jelicic Miloš Tišma

Using cryoEM we understood the structural basis of chiral DNA wrap by bacterial gyrase (and also produced the most complete/highest resolution E coli gyrase model to date). John Innes Centre DurhamUniversity Malopolska Centre of Biotechnology UJ

Hello, I am looking for a #Postdoctoral researcher with experience in bacterial genetics and antimicrobial resistance. Please send me a CV and a brief summary of your lab experience! Thank you!

🇻🇳🎉A sea of red & gold is sweeping through the cities from north to south tonight, as excited fans pour out onto the streets to celebrate the deserved victory of the national football team against archrival Thailand in a thrilling final 🏆⚽ 📸VNA/VNS Photos

Check out what I was up as I was nearing the end of my postdoc! Big congrats and thanks to the cryo-em king casu_b for all the incredible work together and to Susan Schlimpert for letting me work on this project early on until the end of my time there!!!

Join us at The Biology and Physics of Prokaryotic Chromosomes VII to discuss mechanisms of chromosome organisation and structure, chromosome replication, transcription and segregation! Abstract submission deadline 16th July. Register now: ow.ly/2vMA50UF35G

Happy to share our latest work published in Nature Microbiology. A joint effort of Tung Le Darst-Campbell Lab and F. Moreno-Herrero labs. We describe how the KorA-KorB system cooperates to silence genes in a multi-drug resistance plasmid. nature.com/articles/s4156…

Long-range gene regulation in bacteria is rare and often involves DNA looping. Our work reveals an alternative mechanism! Big clap to first authors of this fantastic work: @TomMcLean05, F. Balaguer-Perez, and J. Chandanani @JohnInnesCenter Centro Nacional de Biotecnología (CSIC) Rockefeller University

Happy to share our latest findings on Kiwa. Foundational work from Thomas, with Zhiying and Yi providing beautiful structures and molecular insights. Ever grateful for the collaborations with Eugene and Dinshaw. More to come 🙃 doi.org/10.1101/2023.0…

🚨We are hiring! A MRC-funded PDRA position to study novel anti-phage systems & their evolutionary dynamics in P. aeruginosa, in collaboration with Freya Harrison. If you are passionate about phage-bacteria interactions & evolution, apply now ! tinyurl.com/bddz4z44

New on the Lister Institute blog: How Tung Le and team cracked the mystery of how an important #antimicrobialresistance plasmid regulates gene expression. The researchers reported their milestone in a new paper in Nature Microbiology lister-institute.org.uk/biology-is-ful…

❗️Exciting upcoming post-doc opportunity in the lab❗️🔔 If you have expertise in cryo-EM and bacterial secretion systems are your thing, then I’ll soon be advertising a long-term position funded by Wellcome Trust. Feel free to DM or email for early enquiries.. Thanks!