New Resource out now! Single-cell and spatial atlas of the developing, adult, and aged choroid plexus provides insights into the development and function of this essential brain barrier #neuroscience Lehtinen Lab Boston Children's HMS Department of Neurobiology bit.ly/3ftAmlo

Immune protein's role in the brain: Villeda Lab &co identify a non-canonical role for the classical MHC class I molecule H2-Kb as a negative regulator of neural stem & progenitor cell proliferation, independent of its immune system function #PLOSBiology plos.io/2UPwrYb

I am pleased to present you with a work that has been back and forth with the journals for over 3 years, titled "Microbiota regulate social behaviour via stress response neurons in the brain." This work has finally been published in "Nature". nature.com/articles/s4158…

FXR activation protects against NAFLD via bile-acid-dependent reductions in lipid absorption dlvr.it/S3p6bf

A human apolipoprotein L with detergent-like activity kills intracellular pathogens science.sciencemag.org/content/373/65…

Delighted to share my first (co)first author paper “#Microbiota from young mice counteracts selective age-associated behavioral deficits” out today Nature Aging. Thank you to everyone involved, especially co1st authors Marcus Böhme Thomaz Bastiaanssen, PhD 🧵1/ ... nature.com/articles/s4358…

For many years we have studied nervous system mechanisms that regulate inflammation. A major finding is the vagus nerve inhibits inflammation via acetylcholine. Here we discovered the nervous system can also stimulate inflammation via HMGB1. pnas.org/content/118/33…

In 1895, on turning 50, Elie Metchnikoff became increasingly anxious about ageing.... Read how this influenced our research.. theconversation.com/gut-bacteria-r… via The Conversation

More evidence for Perturbations in Gut Microbiota Composition in Psychiatric Disorders ja.ma/2XnXGe7 This systematic review and meta-analysis found that gut microbiota perturbations were associated with a transdiagnostic pattern via JAMA Psychiatry

Proud of the work by the lab that just came out! We recorded dopamine across a wide range of behavioral tasks and find that dopamine release patterns in the NAc core are best explained by perceived saliency coding and not reward prediction error. cell.com/current-biolog…

Gut feeling about glia: Regulation of intestinal immunity and tissue repair by enteric glia nature.com/articles/s4158…

When you tell an 'omics lab to dress up for Halloween.. Ryan Corces

Primordium is now offering everyone the chance to sample our full-plasmid sequencing service for FREE - never use Sanger sequencing again! Please retweet this message and we'll DM you a coupon to sequence 5 ENTIRE PLASMIDS 100% FREE, no CC or PO needed. primordiumlabs.com 5/

Great time to start tweeting. Happy to share our paper “Interleukin-27 signaling serves as an immunological checkpoint for innate cytotoxic cells to promote hepatocellular carcinoma” finally published in Cancer Discovery Cancer Discovery. 1/1 aacrjournals.org/cancerdiscover…

Now in Cancer Discovery: Interleukin-27 Signaling Serves as an Immunological Checkpoint for Innate Cytotoxic Cells to Promote #HepatocellularCarcinoma Turan Aghayev Aleksandra Mazitova Jennifer Fang Koltsova Lab et al @CSCancerCare Cedars-Sinai Fox Chase Cancer Center National Cancer Institute aacrjournals.org/cancerdiscover…

Does young blood improve cognition and help prevent dementia for people of advanced age? A review of putative mechanisms underpinning the brain rejuvenation hypothesis nature.com/articles/s4159… Nature Neuroscience Villeda Lab UCSF Bakar Aging Research Institute

It seems like it is gonna be wild😉

Excited to share our work out now out in nature ! Villeda Lab UCSF Bakar Aging Research Institute @SCAgingBrain Platelet factors attenuate inflammation and rescue cognition in ageing | Nature nature.com/articles/s4158…

We're excited to announce our recipients of the BARI postdoctoral fellowships! Congrats Jonathan Bayerl Turan Aghayev Coline Arnould Rispal Jérémie, Jery Joy, Kate Cavanaugh, and Gurcharan Kaur!

Evolutionary Medicine, 2nd Ed Will be out in a couple of weeks!