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Higher rates of Tx success for M. absecssus subsp. massiliense vs subsp. abscessus thought be 2/2 to presence of non functional erm41 gene in massiliense DOI: 10.1164/rccm.201003-0395OC

Drug-drug interaction between clarithromycin and rifabutin leads to increased rifabutin levels and is associated with uveitis DOI: 10.1177/106002809502901114

IDSA currently rec daily tx rather than TIW tx for cavitary MAC as TIW tx has been associated with lower than expected sputum conversion rates atsjournals.org/doi/full/10.11…

Younger tx recipient age associated with increased rates of rejection: thought to be 2/2 to decreased med adherence, T cell changes that come with aging pubmed.ncbi.nlm.nih.gov/26965071/

For pulm M. Kansaii tx- fixed 12 months of tx may be enough instead of 12 mo beyond culture conversion. Pooled data from 3 studies only found recurrence rate of ~ 5%. academic.oup.com/cid/article/do…

Continuing 2020 IDSA NTM guidelines: for M. abscessus pulm disease, if macrolide sensitive rec 3 drug regimen, for macrolide resistance recommend 4 drug regimen

Up to 90% of people receiving MAC treatment may experience treatment-emergent adverse events pubmed.ncbi.nlm.nih.gov/30216086/

Happy to be finally fully vaccinated

CDC recommends for those that are vaccinated and then develop COVID-19 that it should not affect treatment decisions such as monoclonal antibodies cdc.gov/vaccines/covid…

Cochrane review: CMV Ig did not reduce risk in SOT when used for CMV ppx. Wide variability in results for various studies though - may be 2/2 to heterogenicity of the precipitants across studies (tx type, immunosuppression) PMID: 17443573

Watching laps 50-51 today at Baku

Yes? 👋 Formula 1

If you're in trouble, he's got your back 👀 We should all try and be a bit more Seb 😇 #BelgianGP 🇧🇪 #F1 Lando Norris

Please RT👍 Come work and learn #TxID with us at UNC. UNC Division of Infectious Diseases Anne Lachiewicz Daphne Villanueva, MD Tyler Lambing Claire Farel Joe Tucker, MD IDEEL @BATLabUNC Joseph Eron @id_bmc Indiana University Infectious Diseases Fellowship IDBugBowl Apply for transplant ID fellowship. Details here: med.unc.edu/medicine/infdi…

Hij gaat naar de top, Max is de nummer 1!!!! 🇳🇱🇳🇱🇳🇱🇳🇱🟠🟠🟠🟠

Secondary ppx for nocardia can be considered but no strong evidence. Hesitation given ⬇️ efficacy of low dose TMP/SMX for primary ppx.

FDA now saying you can do 5 doses (a 2nd booster) for COVID in SOT patients, 4 months after first booster fda.gov/news-events/pr…

Champions league and sonny golden boot 😍

No, you're crying 🥹🥹 #BrazilGP