🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

HEK293 or CHO: which cell line is better to produce difficult-to-express proteins, including heavily glycosylated ones? Interesting remarks. bit.ly/3ivGw5a #glycotime

Apply now to join us for your #PhD 👉imprs-cbp.mpg.de/47910/Call-for…

I am happy to share with you my latest work about dissecting the nuclear import mechanism of a tumor suppressor BAP1, now published in one of my dream journals - Journal of Cell Biology!!! Thank everyone who always supports me, encourages me and inspires me.

In the last 2 years cryo-EM structures have shed new light on the mechanisms of tail-anchored protein biogenesis from insertion to dislocation. Check out our review in Current Opinion/Research in Structural Biology, now online! sciencedirect.com/science/articl…

(1/2) Our work in J. Am. Chem. Soc. is now online. We have determined a novel 4-protofilament amyloid fibril structure using a hamster prion 108-144. The 2.2Å map reveals a clear water wire in the central hole with many typical fibril patterns. IBC Academia Sinica pubs.acs.org/doi/10.1021/ja…

cryoWriter: a blotting free cryo-EM preparation system with a climate jet and cover-slip injector pubs.rsc.org/en/Content/Art…

😂 😂 😂

"The scream of Glacios", September 2022 Description: Sorry, my bad! I shouldn't give you bad samples.

#ModelAngelo is fantastic! I tried a 12mer glutamine synthetase (GS) map (2.4Å) with 1 copy of GS sequence. It generated a perfect 12mer structure (red) with only 0.8 Å (backbone) RMSD to my manually refined structure (blue). (1/3)

one small consolation of turning 60 this year is the ability to submit to 𝘔𝘈𝘛𝘜𝘙𝘌 family journals — sure they’re low impact (for our knees) but they have an early bird special if you submit between 4:00 and 5:30 on weekdays

Apply now! We are looking for a #postdoc to join our membrane protein biogenesis team @MPIBP, combining biochemical reconstitution and cryoET 🧪🥼 For more details and to apply 👉 recruitingapp-5577.de.umantis.com/Vacancies/287/… Please RT

Super highly recommended!!!

#MaxPlanck Art & Science Day - for everyone interested in #science & #art! What is #autophagy? How do our cells recycle their waste? How is research communicated via art? Visit us, learn, explore, be creative! With Dorotea Fracchiolla_Art&Science, Ayelen Valko, Ariane Pessentheiner! 👉biophys.mpg.de/en/max-planck-…

What a beautiful work 🤩

Ooh Wow 😮

☺️🔬❄️

Check out our game, DEGRADATOR! 🎮 Designed to popularize and educate on the ubiquitin-proteasome system and PROTACs. Perfect for kids 12+ but not only 😉 Dive into 10 fun levels to explore protein degradation. Available on Google Play and degradator-game.com 🚀

A new approach from Murphy Lab Olivia Pfeil-Gardiner Filip Van Petegem and colleagues enables elemental mapping in macromolecular complexes, by combining electron energy-loss spectroscopy with single-particle cryo-EM image processing tools. nature.com/articles/s4159…

Our preprint on the first glimpse of how the human proteasome recognizes a K11/K48-branched ubiquitin chain is out. This work reveals a new multivalent ubiquitin binding mode by the proteasome that could serve as priority checkin signal for proteolysis. doi.org/10.1101/2025.0…

Proud to share our first lab pre-print: “SND3 is the membrane insertase within a fungal multipass translocon” where Tzu-Jing Yang solved the structure of a ribosome-associated SND3-translocon complex involved in ER membrane protein insertion ➡️ doi.org/10.1101/2025.0…