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This week, the cell and gene therapy sector saw new notable deals and positive data readouts. #weeklynews #cellandgenetherapy 1/5🧵

3/5 Orca Bio announced positive results from its pivotal phase 3 study of its T-cell immunotherapy and indicated it would seek a 2025 regulatory submission in the US. orcabio.com/orca-bio-annou…

4/5 Novartis published new data demonstrating meaningful efficacy and safety in broad patient populations for its gene therapy to treat SMA. novartis.com/news/media-rel…

I wouldn't have anticipated a Lupus self-directed antibody might someday turn out to be an anti-cancer treatment science.org/doi/10.1126/sc…

This morning in our #stemcell & #genetherapy seminar series we are fortunate to have UCD Health Dept. Dermatology Dr. Sasha Shafikhani Sasha Shafikhani discussing his important work in diabetic wound healing and infection. health.ucdavis.edu/dermatology/fa…

From our outstanding colleague Dr. Maneesh Dave @UCDavis: MSCs mediate long-term efficacy in a Crohn's disease model by sustained anti-inflammatory macrophage programming vi… pubmed.ncbi.nlm.nih.gov/38245543/

A serum- and feeder-free differentiation process, suitable for large-scale production of iPSC-derived CD4sp and regulatory T cells, is reported here. doi.org/10.1093/stmcls…

It has taken decades to get to this point, but stem cells for Parkinson's disease showing promise in 2 clinical trials nature.com/articles/d4158… nature.com/articles/s4158… nature.com/articles/s4158…

Optimizing approaches for targeted integration of transgenic cassettes by integrase-mediated cassette exchange in mouse and human stem cells doi.org/10.1093/stmcls…

Cells differ in their cell-division cycle pace. But only now has it been shown that those types with faster cycles are more susceptible to cancer. nature.com/articles/d4158…

Stem Cells and Female Reproduction: Endometrial Physiology, Disease and Therapy academic.oup.com/stmcls/article…

vimeo.com/1086865887/482… Excited to have been part of this. Always glad to promote UC Davis Aggie Square

Have a look at how research UC Davis continues to impact daily lives and shape our future. #UCDavisDelivers #UCDD #ResearchImpact research.ucdavis.edu/research-progr…

When are we going to see progress for CAR T in solid tumors?", I'm often asked. More to do for sure, but progress is clear. Intracerebroventricular bivalent CAR T cells targeting EGFR and IL-13Rα2 in recurrent glioblastoma: a phase 1 trial Penn Medicine DrORourke

Scientists Urge NIH Director to Restore Research Grants Halted by Trump Administration genengnews.com/topics/transla… via Genetic Engineering & Biotechnology News

To our colleagues and students in #Celltherapy and #Genetherapy, I know MANY of you have submitted applications to move outside of the USA due to the major cuts to NIH funding, and it has seemed hopeless to stay here, due to the "war on science". Please watch this video, give

Support for Research Excellence First Independent Research (SuRE-First) Award (R16 - Clinical Trial Not Allowed) grants.nih.gov/grants/guide/p…

Amazing work from my colleagues in UC Davis Neurological Surgery @ucdavismed Sergey Stavisky David Brandman Maitreyee Wairagkar

Hundreds of NIH grant terminations are ‘void and illegal,’ federal judge rules statnews.com/2025/06/16/nih… via STAT

#NIH released a #FundingOpportunity for the NIH Director’s Pioneer Award to support researchers pursuing bold and innovative approaches to major challenges. Learn more about this exciting initiative: bit.ly/3FYVRKI