
UCL Huntington’s Disease Centre
@uclhd
Committed to training the next generation of scientists and clinicians to contribute to the fight against Huntington's disease 🧬 @UCLIoN
ID: 2898950829
https://www.ucl.ac.uk/ion/research/research-centres/hd-centre 30-11-2014 10:05:55
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Exciting news! Our latest paper is out today in Science Translational Medicine — 'Antisense oligonucleotide–mediated MSH3 suppression reduces somatic CAG repeat expansion in Huntington’s disease iPSC–derived striatal neurons' 🧬 science.org/doi/10.1126/sc… UCL Queen Square Institute of Neurology UCL Brain Sciences

A new study led by Prof Sarah Tabrizi (UK DRI at UCL Queen Square Institute of Neurology & UCL Huntington’s Disease Centre) with Gabriel Balmus has taken major steps forward in advancing genetic therapies for Huntington's👏 The research lays an important foundation for future clinical trials👉buff.ly/4aVcMsN


Curious about brain imaging in Huntington’s disease? Our latest review in Movement Disorders Clinical Practice summarises key findings from structural, diffusion and functional MRI, plus emerging techniques like 7T MRI, MEG and novel mHTT PET radioligands currently under investigation.


Thank you HDYO for the opportunity to talk about HD-YAS at #HDYO Congress 2025! Truly an inspiring community and family — and this absolutely drives all the work we do! UCL Huntington’s Disease Centre UCL Queen Square Institute of Neurology


Hot off the press! Check out the second edition of the EHDN Collaborations Imaging Working Group (#iWG) newsletter! #HD #neuroimaging Michela Leocadi Nicky Hobbs ehdn.org/wp-content/upl…

Check out the March 2025 edition of the #HD Clinical Trials Update, now available online in Journal of Huntington's Disease 🔗 journals.sagepub.com/doi/10.1177/18… UCL Huntington’s Disease Centre UCL Brain Sciences UCL Queen Square Institute of Neurology


Brilliant The Worshipful Company of Pewterers lecture given by Professor Sarah Tabrizi (UCL Queen Square Institute of Neurology, UCL Huntington’s Disease Centre) on ‘Genetic therapies for neurodegenerative brain disorders - where are we now?’.



"Using #NfL concentrations from capillary blood, we replicated previously published disease group differences measured in venous blood. This data supports our #FingerPrick approach for remote collection and quantification of NfL." J of Neuro doi.org/10.1007/s00415… UCL Huntington’s Disease Centre UCL Queen Square Institute of Neurology
