🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

The Song and Ming labs are excited to be here discussing the latest research in Neuroscience at #SfN2023

New research presented by Song and Ming Labs suggests that a tiny strip of brain tissue is one of the few bits of the mouse brain to generate new neurons even in adulthood. They believe this process may hold promise for developing #Alzheimers treatments. spr.ly/6016uLAj2

The time has come to announce the speakers for another spectacular Cold Spring Harbor Laboratory meeting on human brain development and 3D models #organoids #assembloids that I have the great honor to organize with Guo-Li Ming Song and Ming Labs Check out the list and mark your calendar

Hear ye! Hear ye! I report on the first direct evidence of a shared origin of inhibitory and excitatory neurons in the cortex using human postmortem brain tissue, for The Transmitter thetransmitter.org/interneurons/c…

Thrilled to share our review with Song and Ming Labs and Nickzf, delving into the latest advances in brain epitranscriptomics research and its potential translational opportunities! nature.com/articles/s4138…

Throwback to last year’s phenomenal conference at Cold Spring Harbor Laboratory on human brain development #organoids #assembloids — a superb gathering for this new field of multi-cellular models of the human nervous system & disease. Thrilled about organizing another edition with Guo-Li Ming

Attendees from our #Neurogen24 conference embracing the moody skies this morning. It has been fantastic reuniting with many familiar faces from past editions & welcoming new researchers. 3 more days of presentations, networking & hopefully ☀️to come! #Neurogenesis #Neuro

Thrilled to share our new preprint! We leverage GBM organoids and monosynaptic rabies tracing to reveal the brain-wide connectome of this cancer, including a cholinergic neuron-tumor synapse that may fuel GBM invasion. Song and Ming Labs #CancerNeuroscience biorxiv.org/content/10.110…

A new study from Song and Ming Labs reveals an epigenetic mechanism that maintains the quiescence of adult neural stem cells. nature.com/articles/s4146…

#ICYMI: Congratulations to Yusha Sun & Xin Wang (Song and Ming Labs Lab) for winning 2nd place in the NIH BRAIN Initiative Photo Contest for their image, "Chaos circuity"! tinyurl.com/339988ua

🌟 SAVE THE DATE! 🌟 The 4th Neuroepigenetics & Neuroepitranscriptomics Conference is returning with its 4th edition! 🎉 Join us for this incredible event, chaired by Hongjun Song (University of Pennsylvania) and Li-Huei Tsai (MIT), in beautiful sunny St Julians, Malta! ☀️ 💥

Check out our latest work!

(1/2) A new study in nature led by Ce Zhang (Ce Zhang, an alum of Song and Ming Labs) used human brain organoid models to study lissencephaly. They found organoids with genetically distinct disease-causing mutations converge in mTOR dysregulation and nature.com/articles/s4158…

ft. Meghan Logun, Xin Wang, Yusha Sun Stephen Bagley, Nannan Li, Arati Desai, Daniel Zhang, MacLean Nasrallah, Emily Pai, MD PhD, Bike Su Oner, Gabriela Plesa, Donald Siegel, Zev Binder, Song and Ming Labs & DrORourke Penn Neurosurgery Mahoney Institute for Neurosciences @UPenn Penn Medicine - Abramson Cancer Center Penn Path & Lab Medicine cell.com/cell-stem-cell…

British Neuroscience Association help us spread the word about #Neuroepi25! 🌟 Chaired by the incredible Hongjun Song and Li-Huei Tsai, this event is one you won't want to miss! 📅 Dates: 01 - 04 October 2025 📍 Location: St. Julians, Malta For more details, visit: bit.ly/4fZrFey

Super excited to share our recent work now out in nature! We introduce trans-synaptic tracing tools from circuit neuroscience to study the whole-brain connectome of glioblastoma. nature.com/articles/s4158…

By transplanting glioblastoma organoids and performing monosynaptic rabies virus tracing, we find rapid and extensive brain-wide circuit integration of GBM. GBM inputs are highly diverse and include, for example, long-range cholinergic neurons from the basal forebrain.

Monosynaptic herpes simplex virus tracing, immuno-electron microscopy, and functional assays all confirm a cholinergic neuron-to-glioma synapse. Acetylcholine may play a role in GBM invasion via the CHRM3 receptor, which is a potential therapeutic target.

We hope this study provides new tools for the study of #CancerNeuroscience and may eventually lead to a better understanding of this devastating disease.

This has been an incredible journey and I am so grateful for my mentors Song and Ming Labs, an amazing team in the lab Xin Wang, Daniel Zhang, Zhijian, Kristen Park and many more. Special thanks to Minghong Ma, DrORourke, MacLean Nasrallah Emily Pai, MD PhD Penn Medicine