Phase I results of obrixtamig (DLL3-CD3 bispecific T-cell engager) Journal of Clinical Oncology (n=168 SCLC / neuroendocrine carcinoma). Across doses/cohorts, RR 23%, DOR 8.5m (in large cell neuroendocrine, RR 70%). CRS in 57% (G3+ 3%). Active challenger to tarlatamab. ascopubs.org/doi/10.1200/JC…

Spine SBRT, does histology impact local control? Yes, CRC, HCC, Cholang ↓↓LC LC NSCLC, Renal, Sarcoma, Thyroid, Melanoma similar to Breast, Prostate 30/3 LC > 27/3 Highgrade Epidural Dz trend ↑↑ LC w/separation surgery sciencedirect.com/science/articl…

Sean Collins Prostate SBRT @ USF Health I wish all would stop giving the uPSA test. Since ARTISTIC it is unnecessary and is a huge source of anxiety in treated patients. thelancet.com/journals/lance…

Seminars in Radiation Oncology Elsevier is pleased to share "Debate 3: Metastasis Directed Therapy in Oligometastatic Prostate Cancer" by Dr. Maneesh Singh, Dr. Vedang Murthy Vedang Murthy, Dr. Piet Ost Piet Ost sciencedirect.com/science/articl…

Come join me at UPMC Horizon. We are looking for an additional physician to continue to grow our center. Please message me for details upmcproviderjobs.com/job-detail.htm… #radonc ASTRO ACRO - American College of Radiation Oncology ACROresident

Draper Associates invested $1 million in this bold and forward thinking startup, and we committed within the hour. That company is now worth $8.7 billion. Oklo is using nuclear waste to power the planet for the next thousand years. They have permits to restart an abandoned

Always took time to wave or say hi to all of the little guys that proudly wore their Dawgs gear to PNC and headed down to the bullpen to see their guy! I have a feeling a lot of these kids will now be wearing Yankees jerseys! 😔 Thanks David Bednar #dawgsfamily #piratesareajoke

🔔Thanks to Parisa Shams & world expert brachytherapist Sushil for their efforts in bringing us our best #brachy case yet -- FIGO IB3 cervical cancer! Don't forget to check out those brachy volumes & dose constraints in our Contours & Pearls tab! econtour.org/cases/175

Does the addition of MDT to standard of care continuous ADT improve outcomes for oligomet prostate ca? Happy to share the results of EXTEND evaluating this question alongside PI Chad Tang, MD & many others

With its high specificity and its ability to detect huOX40+ activated T cells in vivo, ⁸⁹Zr-ivuxolimab is a promising immuno-PET tracer for imaging human T-cell activation. ow.ly/qKAp50WwqC1 #NuclearMedicine #Immunotherapy #Tcell

Stereotactic body radiotherapy for 152 spinal oligometastases with or without integrated boost, just published Clinical Oncology 2-years OS was 90% 👉SIB resulted in a significantly improved 2-year LPFS 👉Prostate cancer patients showed better outcomes. clinicaloncologyonline.net/article/S0936-…

Focal Boost to the Intraprostatic Tumor in External Beam Radiotherapy for Patients With Localized Prostate Cancer: 10-Year Outcomes of the FLAME Trial | Journal of Clinical Oncology ascopubs.org/doi/abs/10.120…

Long-term results of RTOG 9601 👉🏻 Nearly 20 years of follow-up 💥 Salvage RT + 2 years of bicalutamide = ↓ distant mets 👇🏻 •GS 8–10: ✅ p<0.001 •Positive margins: ✅ p=0.001 •PSA >1.5: ✅ p=0.004 •PSA 0.7–1.5: ❌ p=0.07 (NS) redjournal.org/article/S0360-… IJROBP - The Red Journal

Check out our multi-center retrospective analysis of ablative 5-fraction SMART (Miami Cancer Institute Research) and 15/25-fraction HART (Memorial Sloan Kettering Cancer Center) for unresectable #pancreaticcancer Marsha Reyngold Kathryn Mittauer, PhD Paul Romesser Adeel K Eileen M O’Reilly mdpi.com/2072-6694/17/1…

Congrats Michael Chuong & team! Between 5 fx MR-guided adaptive vs. 15/25 fx CT-guided RT (all ablative w BED ~100 Gy) in LAPC, results favored 5 fx (LC, late toxicity), but promising in both groups. NRG GI011 permits both regimens (w pref for 5 when feasible) – plz enroll 🙏!

Fascinating phase III trial of nasal mupirocin to reduce oral mucositis (OM) in patients receiving radiotherapy (almost all CRT) for NPC. Staph aureus growth on treatment has been implicated in oral mucositis, and we know that probiotics seem to be effective.

Wonderful to have Shauna Campbell, DO as visiting professor AHN discussing spatially fractionated radiation therapy

I would love to talk to anyone interested in joining our Radiation Oncology Network UPMC Hillman Cancer Center! We have several positions available for docs and physicists. Each position benefits from the support of our network with significant academic opportunities for interested

Come join the amazing Uzoma K. Iheagwara, MD, PhD at UPMC Horizon! Or his esteemed colleagues at UPMC Erie, Johnstown, or Uniontown!

Today’s theMednet Search upgrade = faster answers ⚡ Ask full clinical questions—just like you’d ask a colleague—and get expert insights with context. Ex: “When do you use the FAST-FORWARD regimen for breast cancer?” Try it → themednet.org/v2/search/ques… theMednet