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“Ascertaining cells' synaptic connections and RNA expression simultaneously with massively barcoded rabies virus libraries,” describes an end-to-end single-cell RNA-seq based system used to reconstruct cell-type-specific synaptic networks at scale. tinyurl.com/2d62ka6s

Cool looking cell!

Excited to be at #ASMS2021. First and foremost is there a good coffee place nearby!

Deep learning-based features can be used as evaluation metrics. This MCP paper uses phosphosite probability (MusiteDeep), Delta RT and spectral similarity to benchmark different computational pipelines on phosphopeptide data, including FragPipe vs MaxQuant sciencedirect.com/science/articl…

This is so cool: nature.com/articles/s4146…

We can now obtain subcellular maps for both RNA and protein in the same experiment and show the dynamic changes in location of both in the unfolded protein response. Introducing LoRNA (the LOPIT for RNA) biorxiv.org/cgi/content/sh…

Do young and old protein molecules have the same probability to be degraded? Erik McShane and Selbach Lab investigated this question in a beautiful & rigorous study: cell.com/cell/fulltext/…

A new postdoc and my first time attending ACNP. Open to network. Open to any tips and suggestion.

#FragPipe 19 released! New: O-pair site localization for O-glyco. SAINTexpress for interactome scoring. FP-PDV viewer much faster and can show predicted MS/MS spectra. Improved diagnostic ion mining and labile PTM support. PTMProphet works with timsTOF .d. New workflows and more

Hi! Past Travel Awardee here, forced convert to virtual. Check out poster T141 TODAY/TUE if you 💜 neuroplasticity! Vas Dumrongprechachan is doing double-time with this 🔥work co-led with @GoofySynapse and talk tmrw from his PD with Matt MacDonald. #ACNP2022 ACNP

Please come check out our exciting work. Tue Poster - Neuroplasticity and Wed talk - schizophrenia proteomics. Open to chat about cell-type specific subcellular specific proteomics in mice - cortex, striatum, axon development. #ACNP2022 @GoofySynapse Genia Kozorovitskiy Matt MacDonald

Can we perform unbiased discovery of endogenous proteins that traffick from one organelle to another in living cells? Learn about our new proximity labeling method, TransitID, here: Full video of ASCB lecture at tinyurl.com/3dste3am

We are delighted to share our work, now available in nature: nature.com/articles/s4158… Our scoring system can be accessed here: kinase-library.phosphosite.org Coming soon --> the tyrosine kinome and an improved system with many new functionalities & features! #TheKinaseLibrary #KL

My first week of trying to get the Easy nLC to work….

#TeamMassSpec I am new to QE HFX. What do your Hela QC look like for a 75min gradient method with 500ng on EASYspray column? How many PSM and IDs?

Your move University of Pittsburgh thedp.com/article/2023/0…