🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Happy Holidays from Peter van Galen 🎄!! And @SandraMcAllist4 ☺️

1/ My new book 'From Cell line to Command line' is finally here divingintogeneticsandgenomics.ck.page/products/cell-… Grab it to start transforming yourself to a computational biologist! A thread on how this book came into being: 👇🧵

The ability to score cells for good marker genes is most helpful for scRNA-seq cell type annotation. Here are three resources. Further development is warranted 🟣 PanglaoDB panglaodb.se/index.html 🟡 CellMarker bio-bigdata.hrbmu.edu.cn/CellMarker/ 🟢 ABC portal abc.sklehabc.com/#/home

Our 4th place tweet features a paper from the Peter van Galen at Brigham and Women’s Research on a method to help researchers better associate changes in the transcriptional state of cells with #clonal evolution! Check it out: 👇 x.com/ScienceinBosto…

Any help/ideas would be appreciated! Amplified cDNA from 10x Genomics multi-ome gives super high signal around the lower marker on the TapeStation. What could be the issue?

BET inhibitors rescue anti-PD1 resistance by enhancing TCF7 accessibility in leukemia-derived terminally exhausted CD8+ T cells | Leukemia. So excited to see this online!! Tweetorial soon, just landed in Austin, TX for #AACR. nature.com/articles/s4137…

All these in-person meetings are really limiting my ability to reply to emails

I have no words except that I am heartbroken for 2 days.Please consider to help in anyway that you can. Some links that many others shared are below. Thanks everyone who checked in and huge gratitude to those who already contributed a lot of help. #TurkeyEarthquake

HSC vulnerability to ferroptosis is exacerbated by attenuating protein synthesis via MYSM1 loss, downregulation of translation initiation and ribosomal genes, and differential effects on translation of specific transcripts. Congratulations Vijay Sankaran and ZHAO Jiawei!

Targeting mitochondrial dysfunction in acute myeloid leukemia ⁦Leukemia Journal⁩ nature.com/articles/s4137…

Some of my favorite people in the field 😁 great choices ISEH Congratulations Peggy Goodell Daniel Starczynowski Nina Cabezas-Wallscheid 🪅

Peter van Galen second generation / prior to some changes - what a privilege to work with this group!

Very happy with this commentary on a great paper where Yoke Seng Lee and I distilled down the key messages. Enjoy reading! authors.elsevier.com/a/1h3Uz_9T5tl20

Super proud and thrilled that this paper is out! 📃 Many thanks to the fantastic team - I’ll fondly remember the lengthy discussions to extract the deepest biological insight using the samples and assays available to us 🧬🥳

Fantastic new work on clonal hematopoiesis and progression to leukemia w additional environmental factors! 🤩 #TET2 biallelic muts, resistance to cell death, UV exposure… Soup-to-nuts read. Congrats all! Will be a classic. 👏👏👏

.Peter van Galen hike at Walden Pond 🥾 what an honor to work with this amazing team!

Very delighted to share our work Deciphering cell states and genealogies of human hematopoiesis online today in nature (Accelerated Preview version). It is a really great collaboration of Weissman lab Jonathan Weissman's Lab and Sankaran lab Vijay Sankaran doi.org/10.1038/s41586… 🧵(1/n)

Come join a more sympathetic alternative to 𝕏 → bsky.app/profile/vangal… I'm hoping to see more members of our scientific community soon ❤️ Read more: techcrunch.com/2024/02/06/blu…

Congratulations on your award Nurefsan Sariipek, MD! Impressively self-driven and well-deserved to support your innovative work 🎈

There has been confusion over mitochondrial mutation detection, consensus variant calling, and lineage tracing in single cells. Here, we detail how ReDeeM addresses these challenges, improving detection of mtDNA mutations by 10-fold and lineage tracing. Led by Chen Weng and