Mitochondrial cardiomyopathies This review discusses comprehensive overview of the pathophysiology, clinical features, diagnostic approaches, and treatment options for mitochondrial #CMP academic.oup.com/eurheartj/adva… #CardioEd EHJ Editor-in-Chief European Society of Cardiology Journals

Medicare beneficiaries who use palliative inotropes have high rates of admission and low use of palliative care services. There is a need for better integration of palliative care services into heart failure care. #AHAJournals Sarah Chuzi, MD, MSc ahajrnls.org/3He4Zfa

🚨 New in Heart Rhythm! We compared pulsed field ablation (#PFA) vs. radiofrequency ablation (#RFA) for #PVI (pulmonary vein isolation) in paroxysmal AF. What happens to left atrial function after #PFA vs #RFA? The answer might surprise you. 🧵👇 🌟Wouter L’Hoyes | #LVerhaeghe🌟

The modern cardiovascular drug development landscape has been largely shaped by human genetic studies. Emerging IL-6 targeting therapies are a landmark example. In this Circulation: Genomic and Precision Medicine paper with the Tourmaline Bio team (developing an anti-IL6 antibody for atherosclerotic

A light Sunday read for those interested in how genetics can inform drug development: from target selection to prioritizing indications, informing repurposing strategies, optimizing trial design & detecting safety signals 🔗link to paper (🔓open access): ahajournals.org/doi/10.1161/CI…

🚨 Hot off the press: JACC Advances SGLT2i ↓ myocardial glucose uptake on FDG-PET: ▪️ 374-pt matched cohort ▪️ “No uptake” in 65 % on SGLT2i vs 37 % controls ▪️ Total myocardial glycolysis ⬇️ despite ↑ prescan glucose Metabolic shift may underlie CV benefits & carries

“It’s an opportunity for heart failure doctors to differentiate ourselves… This could be a whole year of training.” – Dr. Eric Adler on integrating genetics into advanced heart failure care Learn why gene therapy may redefine the... Priya Umapathi hfsa.org/heart-failure-…

🚑BREAKING NEWS. This is massive. 10 year PARTNER 2 data has been released by the company. No statistical analyses were performed. But I performed them and these is what happened at 10 years. Patrick Myers Rafa Sádaba The Society of Thoracic Surgeons EACTS

High blood pressure is the most prevalent and modifiable risk factor for the development of cardiovascular diseases, including coronary artery disease, heart failure, atrial fibrillation, stroke, dementia, chronic kidney disease, and all-cause mortality. This reflects several

In adults with a hypertensive emergency (BP >180 and/or >120 mm Hg and evidence of acute target organ damage), admission to an intensive care unit is recommended for continuous monitoring of BP and target organ damage and for consideration of parenteral administration of

The CSPACE trial supports the indication of CSP as an upfront pacing technique for pts with AV block. CSP: 🟡lower PICM 🟡 lower need for biventricular CRT upgrade 🟡 higher requirement for lead revision compared to RVSP 🟡 no difference in HFH or mortal jacc.org/doi/abs/10.101…

Hot off the press! Check out the August edition of Circulation: Genomic and Precision Medicine 📖featuring the latest original articles, research letters, & reviews, from everything from cardiomyopathy❤️to aortic disease & pulmonary 🫁 HTN ahajournals.org/toc/circgen/cu… AHA Science #AHAjournals #CardioTwitter #Genetics

For a deep dive into HF therapies approved over the past decade. 👇🏻 jacc.org/doi/full/10.10… JACC Journals

Heart failure affects more than 55 million people worldwide. 🫀 A new Lancet Series, presented at #ESC2025, serves as a call to action for clinicians, health systems, and governments to prioritise the primary prevention of heart failure. hubs.li/Q03G8nPK0

1/ From Supraja Kadagandla + Ashish Kapoor + team: Identification and Functional Assessment of Candidate Causal Cis-regulatory Variants Underlying Electrocardiographic QT Interval GWAS Loci ahajournals.org/doi/10.1161/CI… AHA Science #AHAjournals #CardioTwitter ...

Building on the legacy of many, I'm incredibly excited that we have successfully translated our polygenic risk scores into a validated clinical assay Mass General Brigham Broad Institute, orderable by any clinician in the US today. 🧬To order: massgeneralbrigham.org/en/research-an… 🧬Announcement:

From Drs. Bhattacharya and Natarajan + team: Importance of Clinical, Laboratory, and Genetic Risk Factors for Incident CAD doi.org/10.1161/CIRCGE… AHA Science #AHAjournals #CardioTwitter Pradeep Natarajan Mass General Heart Mass General Brigham Research 📽️ @vibhuparcha

From Ms. Jordan and Dr. Hershberger + team - Implementing Precision Medicine for Dilated Cardiomyopathy: Insights from The DCM Consortium doi.org/10.1161/CIRCGE… AHA Science #AHAjournals #CardioTwitter Ray Hershberger The Ohio State University Wexner Medical Center 📽️ @vibhuparcha

🧵Family screening in DCM – What cardiologists need to know 🧬🫀 New ESC clinical consensus on managing family members of patients with Dilated Cardiomyopathy (DCM) #Cardiology #CardioEd #Genetics #DCM Tailored screening & genetics are the key 🧩👇

A long-awaited consensus statement on inflammation and heart disease "We have thus entered an era when the evidence linking inflammation with ASCVD is no longer exploratory but is compelling and clinically actionable." JACC Journals open-access jacc.org/doi/10.1016/j.…