🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

During immune homeostasis, dendritic cells become tolerogenic in the spleen by consuming cholesterol from apoptotic cells or lipid nanoparticles, new research by Victor Bosteels Sophie Janssens Lab in mice finds. Read more: scim.ag/2Bs

(1/12) 🚨 For all DC lovers out there, 📢our paper on homeostatic dendritic cell maturation is finally out! Science Immunology science.org/doi/10.1126/sc… In this paper we're shedding light on the poorly understood process of homeostatic DC maturation🧵

New work by Victor Bosteels Sophie Janssens Lab demonstrates how conventional type 1 dendritic cells mature in mouse spleens in the absence of infection. scim.ag/2Ey

Come find SaeysLab at #CYTO2023! 2/2 🛠️workshops🛠️ Sunday 15:45 room 510A - Data preprocessing in cytometry Tuesday 15:45 room 511D - Teamwork makes the dream work Fill out the survey about teamwork here: bit.ly/3GXQPva or use the QR code below ⬇️

#CYTO2023 last call to fill out our survey on collaborations between bio-informaticians, wet-lab scientists and SRL 👉 bit.ly/3GXQPva We currently have 71 responses. Help us reach 80! 🙏 See you tomorrow in our workshop! 🛠️15:45 room 511D ISAC

Happy to share our collaborative work with Sophie Janssens Lab!. Long story in the making but finally is out and our groups are proud: Nuanced role for dendritic cell intrinsic IRE1 RNase in the regulation of antitumor adaptive immunity. doi.org/10.3389/fimmu.…

We are thrilled that our recent study lead by @BayerlFelix is out in Immunity today. We addressed the question how cDC1 dysfunction is regulated in tumors and to which extent this contributes to cancer immune evasion. It is Open Access!👇 cell.com/immunity/fullt… A short 🧵:

(1/18) We present NicheNet-v2 and MultiNicheNet, two improvements to our NicheNet ecosystem for studying cell communication. NicheNet-v2 is an update of our ligand-receptor-target model. MultiNicheNet is a new tool for differential communication analysis. doi.org/10.1101/2023.0…

New in Journal of Experimental Medicine: Bastiaan Maes, Sophie Janssens Lab, bart lambrecht et al. UGent reveal an unexpected role of TAOK3 in regulating ST2+ regulatory T cells in mouse adipose tissue. Absence of TAOK3 sustains Tregs in #obesity and improves metabolic dysfunction. bit.ly/3XjLTI0

The ever expanding universe of TAOK3…Very proud that this joint study with bart lambrecht got published. Big congratulations to Bastiaan Maes and Farzaneh Fayazpour for a massive amount of work!

3... 2... 1... Registration for our Computational Cytometry Summer School is now open! 🎉 Run to 👉training.vib.be/all-trainings/…👈 to find the program and register before November 30th Big 🙏 to our sponsors Dotmatics FlowJo

Interested in dendritic cell biology and/or IRE1 signaling? Ready for a new challenge in the city of Ghent? If the answer is 2x yes, please check the VIB website for open positions for a PhD student jobso.id/har5 and a postdoc jobso.id/har8 in the Sophie Janssens Lab

Check our paper on Automated antibody dispensing! All single stains, FMOs and full stains pipetted in under 20min! The I.DOT DISPENDIX makes it work. #flowcytometry #automation #spectral Thx to Victor Bosteels and VIB Flow Core Ghent team.onlinelibrary.wiley.com/doi/full/10.10…

Making your antibody mixes in less than 20min using amazing technology! These are the results of a nice collaboration with VIB Flow Core Ghent

All’s well that ends well. 3.5 days of intense discussion at our lab retreat, punctuated by social interactions. And the obligatory pool photo!

Excited to share that the review article I wrote together with Sophie Janssens Lab on the latest insights in homeostatic DC maturation has just been published! Check it out here: rdcu.be/dUdp0 #DendriticCells

Excited to share that our story on apolipoprotein control of cross-presentation is now published in Science Immunology and can be found here science.org/doi/10.1126/sc… Congrats first authors Gerone Gonzales , Liam Wilkinson and Song Huang, as well as Cassie Wood and xless authors too. 😊

Have a look at our new #preprint on Research Square: Early life RSV infection as a preventable risk factor for asthma researchsquare.com/article/rs-536… Contains epidemiology on entire Danish population, 24000 hospital admissions for RSV and causality experiments in mouse model