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Join us on Friday December 15th, for our GMaC Seminar Series to learn more about " Mapping the Cellular Determinants of Genome Editing in Human Cells" from Britt Adamson, PhD, from Princeton University.

Happy Holidays from the Vindigni lab! I am so grateful to work with an amazing group of young scientists!!! ⁦Siteman Cancer Center⁩ ⁦Test Account⁩

Join us on Friday January 19, for our GMaC Seminar Series to learn more about “Mining for Gold with AlphaFold: Lessons from Genome Maintenance” from Johannes Walter, PhD, from Harvard University and HHMI.

.Alice Meroni, Sophie Wells, Fonseca et al. show that DNA combing resolves sister chromatids, allowing the detection of strand-specific alterations, whereas DNA spreading typically does not. hubs.ly/Q02jQq4l0 Vindigni lab Keith Caldecott Arnab Ray Chaudhuri #DNABiology

My new colleague in the Center for Genome Integrity! Psyched that John joined us in St. Louis!

Not only the Science is TOP at the #EMBOdnaDamage in #Lonavala but venue is an oasis and food is incredible !!! And one person made it all possible... Thank you Arnab Ray Chaudhuri 🙏🙏🙏

Center for Genome Integrity St. Louis team at the exciting #EMBO DNA repair meeting in my home country #INDIA Vindigni lab thanks Arnab Ray Chaudhuri for organizing this wonderful meeting #AmazingSceince #Scenery #Food!!! @WUSTLdbbs Siteman Cancer Center

Wonderful presentation by ⁦Isabelle (she/her)⁩ at CGI retreat on exciting new research on DNA repair in BRCA1-deficiency.⁦Center for Genome Integrity⁩ ⁦Siteman Cancer Center⁩ ⁦@WUSTLdbbs⁩ ⁦@WashUOnc⁩ ⁦@WUDeptMedicine⁩

The Vindigni lab had a blast at the 3rd annual CGI retreat at Cedar Creek Lodge! There were exciting talks and posters by trainees from WUSTL and SLU! ⁦Center for Genome Integrity⁩ ⁦Siteman Cancer Center⁩ ⁦Test Account⁩ ⁦@WUSTL⁩ ⁦@WashUOnc⁩ ⁦⁩ ⁦Saint Louis University⁩

A huge thank you to CGI Retreat invited speaker Ryan Barnes (University of Kansas Medical Center) and keynote speaker Tanya Paull (University of Texas at Austin) for their amazing talks! So glad you could join us!

Join us on Friday April 19th, for our GMaC Seminar Series to learn more about "Replication initiation and genome evolution." from Julian Sale, PhD, from Division of Protein & Nucleic Acid Chemistry, MRC Laboratory of Molecular Biology.

Join us on Friday May 24th, for our GMaC Seminar Series to learn more about “Concentration matters: Ribosome function beyond protein synthesis” from Rachel Green, PhD, from Johns Hopkins University, HHMI.

Dr. Alessandro Vindigni Vindigni lab is the Ira Lang Professor of Medicine. Dr. Vindigni is a Professor of Medicine and Pathology & Immunology, Director Center for Genome Integrity Test Account and Co-leader of the Section of Molecular Oncology @WashUOnc More> internalmedicine.wustl.edu/dr-alessandro-…

Drs. Valerio Rasi, Zach Grese, Jess Bourque, Emily Cybulla , and Meghan Murray 2024 graduates of the MD PhD program. Best Wishes for each of you, your dedication and compassion will make a difference for so many. Congratulations!

Congrats the Abby Green for their recent publication in EMBO- The SMC5/6 complex prevents genotoxicity upon APOBEC3A-mediated replication stress. Check it out! pubmed.ncbi.nlm.nih.gov/38886582/

Congrats the priyanka verma lab on their recent publication! Nucleolytic processing of abasic sites underlies PARP inhibitor hypersensitivity in ALC1-deficient BRCAmutant cancer cells. Check it out! nature.com/articles/s4146…

The Vindigni, Krais and priyanka verma labs had an amazing time walking the STL Ovarian Cancer 5k this weekend! It was inspiring to connect with the community we hope to serve with our science 💪🏃‍♂️Siteman Cancer Center Center for Genome Integrity WashU Medicine Division of Oncology WashU Medicine

The Vindigni lab social media is moving to other places! Follow us at @vindignilab.bsky.social