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Congratulations Vishwa Deep Dixit and team!! How cool it is for a single amino acid cysteine to completely change organismal metabolism!!! 🤩🥳👏👏 Yale Center for Research on Aging (Y-Age) Yale Pathology Yale School of Medicine “Cysteine depletion triggers adipose tissue thermogenesis and weight loss” nature.com/articles/s4225…

Taurine, an amino acid once considered a biomarker for human aging and a candidate for supplementation, shot down Science Magazine science.org/doi/epdf/10.11…

Wow! “Cysteine depletion or deprivation triggers adipose tissue thermogenesis and weight loss”. Elegant, sophisticated and important! Kudos Dr. Lee and Dixit!!! #ScienceMatters nature.com/articles/s4225…

A study in Nature Metabolism describes how reduced dietary availability and systemic loss of cysteine leads to adipose tissue browning and rapid weight loss in mice and humans. go.nature.com/442dd2p

Developmental trajectory and evolutionary origin of thymic mimetic cells nature nature.com/articles/s4158…

What’s up with Taurine? New bioRxiv suggests elevated taurine caused by caloric restriction serves as a hormetic stress that lowers age-related inflammation — and can protect mice against death from a bacterial infection 🤔

Here’s the paper biorxiv.org/content/10.110…

Removing a certain amino acid from your diet may induce weight loss. A high-fat diet will typically cause weight gain — but a new Yale study has uncovered an unexpected biological loophole that turns fat storage into fat usage: bit.ly/3Tda6hW #Yale

The NIH highlight of our study showing that cysteine depletion triggers adipose tissue thermogenesis and weight loss. These findings suggest strategies to improve metabolic health without restricting calories. bit.ly/44nseMr

Based on studies in mice the Scherer lab highlights the potential of FGF-21 for treating metabolic syndrome and age-related diseases by promoting a healthier metabolic profile under dietary stress and extending healthspan and lifespan Cell Metabolism cell.com/cell-metabolis…

New content online: Cysteine deficiency induces rapid weight loss via adipose tissue browning bit.ly/3HYRqjH

Yale's Vishwa Deep Dixit lab sheds light on how amino acid metabolism directly influences adipose tissue function and browning Nature Reviews Endocrinology #metabolism #obesityresearch rdcu.be/ethbf

A genetic modification that causes mice to overexpress a particular hormone prevents them from gaining weight and allows them to live longer go.nature.com/3Tfa8Gm

Hormone (FGF21) helps mice live longer and avoid obesity nature.com/articles/d4158… #metabolism #obesity #aging

“Immunometabolism Across Scales: From Cells to Systems to Healthspan” will be held Jan. 11-14, 2026 in Vancouver BC. Scientific organizers include Vishwa Deep Dixit of Yale School of Medicine. They meeting will explore the critical junction of metabolic & immune processes bit.ly/4nAdYYA

RESEARCH | AH Lee, Vishwa Deep Dixit et al. (Yale School of Medicine): Reduced dietary availability and systemic loss of cysteine leads to adipose tissue browning and rapid #weightloss in mice and humans 🐭👥 nature.com/articles/s4225…

Excited to share our latest work out now in print nature! Lead by @almudena_Chaves and @ScottMillman_MD, we uncover how metabolic rewiring via OGDH controls tissue regeneration and stem cell fate in the intestine 🚀🚨 bit.ly/44oaOiW

Honored to be working with Kaechlab (Sue Kaech) and Vishwa Deep Dixit to organize Keystone Symposia #Immunometabolism Across Scales, this October! Join us to explore emerging research in Vancouver! keysym.us/KSImmunometab26 #KSImmunometab26 I'll be posting updates!!

#aging #immune_aging NEW PREPRINT FROM Artyomov&Randolph labs: How mouse age-associated GZMK+ CD8 Taa cells develop and what are correct surface markers for them biorxiv.org/content/10.110… Among other things we - Using OT1-Rag2ko mice explicitly show the TCR dependence and yet

“Immunometabolism Across Scales: From Cells to Systems to Healthspan” will be held Jan. 11-14, 2026 in Vancouver BC. Scientific organizers include Vishwa Deep Dixit of Yale School of Medicine. The meeting will explore the critical junction of metabolic & immune processes bit.ly/4nAdYYA