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Pleased to share our paper about addition of new myonuclei during exercise. Lots of credit to Qing Goh and rest of team! Essential collaboration with Sakthivel Sadayappan, PhD, MBA for analysis of muscle function. eLife - the journal doi.org/10.7554/eLife.…

First-year MD/PhD student wins 250,000 award. bit.ly/2PF6eVH

Read our recent paper where we identify the ordered oligomeric species of #TDP43, which form at the initial stage of #aggregation. We show that this process occurs through the RRM domains and can be disrupted by #RNA binding. #ALS #FTD #SLU #STL Saint Louis University

CU MSTP Isabel Fernandez making waves! cuanschutztoday.org/new-disease-di…

Whoa. The gut #microbiome of elite athletes (marathon runners) has a bacterium that enhances performance, makes mice run longer, and this is mediated via lactate metabolism Nature Medicine nature.com/articles/s4159… (file under more #microbiome amazing stuff)

Here's our "mice in space" project. In contrast to all earth-bound models, low gravity still induced atrophy in MuRF1 gene knockouts, demonstrating that this form of atrophy is distinct from muscle loss on earth: nature.com/articles/s4159…

Nuclear hnRNPA2B1 initiates and amplifies the innate immune response to DNA viruses science.sciencemag.org/content/early/…

Only 1.5% of medical doctors are engaged in scientific research. It's time (long overdue) to do something about that. nytimes.com/2019/09/23/opi… New York Times Opinion by Mukesh Jain CWRU School of Medicine and colleagues @the_pssf

FUS-mediated regulation of acetylcholine receptor transcription at neuromuscular junctions is compromised in amyotrophic lateral sclerosis: nature.com/articles/s4159…

The views around CU Boulder 🦬 are unbelievable right now. 🏔😍❄️

A potential protective mutation for a very severe, familial (PSEN1) form of #Alzheimers: the value of sequencing people of extreme phenotypes, resistant to penetrance Nature Medicine nature.com/articles/s4159… @ytquiroz @MGHmapp MassGeneral News and colleagues

It’s always great to see two fields come together to discover something exciting!

Our (co-inventors Jason McLellan) COVID-19 vaccine (spike delivered by Moderna's mRNA) was just injected into the 1st human in phase 1 trial, only 66 days after viral sequence release... a testament to rapid vaccine development for emerging diseases🦠💚 niaid.nih.gov/news-events/ni…

Nice! This will be important for redeploying workers, especially in healthcare

John Prine, one of America’s greatest songwriters, has died at age 73 from coronavirus complications rol.st/2JP2EG8

It will be interesting to look at these variants in patients with severe COVID19

Studies suggest blood clots appear in 20% to 30% of critically ill COVID-19 patients. Scientists have a few hypotheses to explain the phenomenon, and they are just beginning to launch studies. But they are also scrambling to test clot-curbing medications. go.nature.com/2YGUuIG

When USMLE q-banks want to imply that the patient in the question stem is under intense emotional stress or actively having a psychotic break they just combine “graduate student” and “thesis.” These are easy points for MD/PhDs…too easy