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Mitochondrial dysfunction causes redox stress that inhibits proteasomal degradation of HIF-1α to promote the transcriptional and metabolic programming of terminally exhausted T cells nature.com/articles/s4146…

Happy Halloween! WüSI - Systems Immunology Würzburg’s scientists embraced the spookiness with pumpkin carving, scary cookies, a costume challenge, a PI pipetting competition ;-) karaoke and spooky dance moves. We wish you all a spine-chilling time and lots of fun celebrating Halloween. Pic: Xless Vaeth lab

🚨🆕"What if we could map viral infections in 3D?" Now we can! Discover our #clickVSV technology in our latest publication ACS Nano: ▶️pubs.acs.org/doi/10.1021/ac… A joint effort of the labs of Georg Gasteiger and Gerti Beliu at Universität Würzburg #UniWürzburg #Virology #VirusResearch #Science

Check out this new Nature Communications publication by Martin Vaeth from WüSI - Systems Immunology Würzburg. 👇 Congratulations to all authors! 👏

Fluorescent viruses (magenta) infecting cells (white) - live! 👇 #LatticeLightSheet #Fluorescence #SARSCoV2 #Covid #research #biotech #infection

Circulating NK cells establish tissue residency upon acute infection of skin and mediate accelerated effector responses to secondary infection dlvr.it/T1ByqF

Great opportunity, exiting project, PI and environment: come and join Jakob Zimmermann to study T cells and the microbiome WüSI - Systems Immunology Würzburg

Ha! AI models require data on genuine human interactions , or they collapse! disq.us/t/4pugllq

We congratulate Dr Jakob Zimmermann on the #ERCStartingGrant! He is investigating the interaction between intestinal flora and the immune system @wue_si. Jakob Zimmermann European Research Council (ERC) uni-wuerzburg.de/en/news-and-ev…

Reinforcement for the Max Planck Research Group of Systems #Immunology WüSI - Systems Immunology Würzburg Universität Würzburg #UniWürzburg: #ERCStartingGrant winner Jakob Zimmermann is launching his team here. He investigates the interaction between intestinal flora and the immune sy nachrichten.idw-online.de/2024/09/11/erc…

Welcome Jakob Jakob Zimmermann and congrats to the European Research Council (ERC) grant, the WüSI - Systems Immunology Würzburg team is excited to have you on board!

Jetzt in der Mainpost 😊. Dank geht raus an Christina Bornschein, Robert Emmerich und alle anderen Beteiligten von Universität Würzburg #UniWürzburg und WüSI - Systems Immunology Würzburg für das Engagement bei Text und Verbreitung! mainpost.de/regional/wuerz…

Excited to share our new paper in Journal of Experimental Medicine 🎉 We show that NK cells use autocrine TGF-β1 signalling to establish tissue residency, form a highly cytotoxic subset, and protect the tissue against viral persistence. rupress.org/jem/article/22…

Tissue-resident NKs in glands depend on their own TGFb! Congrats Colin and Sonia TuguesLab - great work! and stimulating discussions - thanks a lot!

Differentiation of tissue-resident NK cells: Why origin and context matter cell.com/immunity/fullt… Free access: kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F%2…

A second priming phase promotes high-affinity CD8 T cells by coordinating CD4 help and the relay of IL-2 in subfollicular LN niches. Congrats to WüSI - Systems Immunology Würzburg’s Kasia, Deeksha, Kastenmüller Lab Georg Gasteiger . science.org/doi/10.1126/sc…

#Immunology out now Science Magazine After initial priming in the lymph nodes, mouse CD8 T cells undergo a second phase of stable interactions with dendritic cells that can preferentially stimulate those with a high-affinity for antigen. buff.ly/lCPsea3 By Jobinet al.

Imaging the Immune System! Amazing line-up at the 6th Edition of this International Meeting. Join us June 11-13 for Wine and Science at the historic Julisuspital in Würzburg, Germany imaging-immune-system.wuesi.com

Seeing is believing! Few spots left for Imaging the Immune System—the 6th edition of this world-class meeting. Don’t miss the amazing speakers, wine, and science 🍷🧬 📅 June 11–13 📍 Historic Juliuspital Winery, Würzburg, Germany 👉 imaging-immune-system.wuesi.com

We have an attractive opening for a tenure-track professorship in Single-Cell Systems Biology. Excellent package and infrastructure at the Institute of Systems Immunology WüSI - Systems Immunology Würzburg. Great place to live and work in the heart of the franconian wine region! jobs.sciencecareers.org/job/673667/jun…