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Check out the new paper Angewandte Chemie by Ferrier's "Fungal Factories" team! They described the full biosynthetic pathway that delivers the structurally complex Nodulisporic acid A, a potent insecticide, and related compounds. MBIE Science Wellington UniVentures onlinelibrary.wiley.com/doi/10.1002/an…

Check out the latest paper in press Journal of Biological Chemistry from Ferrier’s chemical and synthetic biology team! “Conformational interdomain flexibility in a bacterial α-isopropylmalate synthase is necessary for leucine biosynthesis” Marsden Fund jbc.org/article/S0021-…

Glad to see this paper out in press Journal of Biological Chemistry🎉great teamwork😊using MD simulations and experiments we studied dynamics and allostery in a bacterial enzyme key for Leu biosynthesis. MD simulations ran NeSI, SAXS Australian Synchrotron, funding Marsden Fund. jbc.org/article/S0021-…

Check out the latest Ferrier publication, a review on "Structure, mechanism and inhibition of anthranilate phosphoribosyltransferase" published in Philosophical Transactions of the Royal Society B: Biological Sciences. Royal Society Publishing royalsocietypublishing.org/doi/10.1098/rs…

Great teamwork combining synthesis, testing and modeling in this paper🎉 Very pleased to show the modelling results used to explain some of the trends observed in the testing results in this new class of compounds targeting TGR5 receptor. Read more here authors.elsevier.com/c/1gejLoqiQEXW…

The Grinter lab is now accepting formal applications for a Research Fellow. If you have a passion for molecular biology and want to discover the next generation of antibiotics, apply below. Please retweet to spread the word. timeshighereducation.com/unijobs/listin…

Autumn 🍂

Very pleased to play a small part in this exciting new study☺️congratulations to everyone involved in this work🥳

Super excited to be part of the team! Looking forward to more of the cool science 😎

Just voted for the Fantail for Bird of the Century birdoftheyear.org.nz/fantail

Delighted to contribute to this study – big congrats to all involved! 🎉 It's amazing to see the collective effort pay off.👏

I see my tired reflection

We have been very saddened to lose three great chemists in recent months. In CiNZ (online) we remember Professor Leon Phillips, Dr Ashley Wilson, and Dr Albert (Jim) Ellis for their inspiring careers and significant contributions to the NZIC. cinz.nz/categories/obi…

"Papers and peer reviews with evidence of ChatGPT writing" Great initiative by Retraction Watch, with the real kudos going to Guillaume Cabanac ⟨here and elsewhere⟩ buff.ly/3vird9P

Happy to see this paper published, featuring my QM calculations for small molecules 🎉 This has been an interesting shift from my usual enzyme research and further expanded my computational expertise. Grateful to my collaborators for this opportunity to venture into new areas☺️

Thanks Ivan😊 and thanks Biomolecular Horizons 2024 for the opportunity to present my research, it’s been a great conference. I’m really happy to meet collaborators and make new friends here☺️ #BMH2024

lol

Apparent reversal of allosteric response in Mycobacterium tuberculosis MenD reveals links to half‐of‐sites reactivity …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/cb…

Identification of novel inhibitors targeting serine acetyltransferase from Neisseria gonorrhoeae sciencedirect.com/science/articl…