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Metal hydride reductions join the growing family of reactions catalyzed by metalloenzymes! Check out this paper on abiotic reactivity, achieved on a carbonic anhydrase platform. Kudos to Pengfei Ji, Jeeyoung, and Yang! nature.com/articles/s4155…

We reconstitute active artificial hydrogenases using apo-protein of [Fe]-hydrogenase and synthetic Mn complexes. The most active variants appear to operate via a reaction pathway deviated from the native pathway. onlinelibrary.wiley.com/doi/10.1002/an… EPFL Chemistry Angewandte Chemie

It's my great pleasure to announce that I'm going to start a professorship and research group in Synthetic Microbiology at the University of Regensburg as of this summer. After an exciting 10+ years in the Panke Lab at D-BSSE, ETH Zurich it's time for new adventures! 🧬🧫🔬💻

JACS online: An Artificial #Metalloenzyme Based on a #Copper #Heteroscorpionate Enables sp3 C–H #Functionalization via #Intramolecular #Carbene Insertion University of Basel Ward Group Total Synthesis J. Am. Chem. Soc. Top Science @CHNSci Total Synthesis and Methodology Highlights pubs.acs.org/doi/10.1021/ja…

Anyone interested in joining the Ward group for a PhD? Have a look at euraxess.ec.europa.eu/jobs/851522 and x.com/MetRaZymes for an opening as part of an exciting team of European chemists

Congratulations! also to the Swiss National Science Foundation starting grant...

This Chemical Reviews was guest edited by #NCCRCatalysis PIs Thomas Ward Group and Christophe Copéret Group / @coperetgroup.bsky.social! The issue focuses on "Bridging the gaps: Learning from Catalysis across Boundaries" - right up our alley! 🧪📑 Read here 👉🏻 doi.org/10.1021/acs.ch… x.com/CoperetGroup/s…

We are thrilled to share a new HF-free technology that converts fluorspar to fluorochemicals. Enormous congratulations to the amazing team of chemists who made this recurring dream a reality! science.org/doi/10.1126/sc… Cal Patel Science Magazine Oxford Chemistry FluoRok

Artificial Metalloenzyme-Catalyzed Enantioselective Amidation via Nitrene Insertion in Unactivated C(sp3)–H Bonds | JACS University of Basel Ward Group Total Synthesis and Methodology Highlights #Metalloenzyme #Enantioselective #Amidation #Nitrene #CHfunctionalization pubs.acs.org/doi/10.1021/ja…

Celebrating Rudy Marcus’ 100th birthday ⁦Caltech⁩ ⁦Caltech Chemistry & Chemical Engineering⁩ ⁦The Nobel Prize⁩ . Still loving #chemistry!!

Great collaboration A big thank you to all contributing colleagues/authors/experts and Jo Richers for a superb title page

ever since Lena Barra's work on PLP-mediated catalysis in the biosynthesis of altemicidin, I've been fascinated by PLP. very cool to see this enzymatic pathway intercepted by photoredox-generated radicals!

Nice work! ✨ nature.com/articles/s4155…

Congrats to Tobias for the nccr tubo grant!

We have a PhD position opening for a candidate with demonstrated experience in electrochemistry. We are aiming to immobilize various metalloenzymes for small molecule activation. See for example: pubs.acs.org/doi/ful

Now online: News & Views on the Article by Zhi Zou, Thomas R. Ward & co-workers Ward Group University of Basel nature.com/articles/s4416… ($) Microbial cell factories for cycloalkene synthesis by Ru Jiang & Gerard Roelfes Roelfes Group (find us as @roelfesgroup on BS) nature.com/articles/s4416… ($)

Large-scale, automated screening and active machine learning can increase the success rate and efficiency of enzyme engineering NEW #ASAP by JeschekLab, Andreas Krause, Ward Group & colleagues Read it here: go.acs.org/a28

Enzyme repurposing of Carbonic Anhydrase and Myoglogin into… ketoreductases. Check out John Hartwig’s paper in Angewandte Chemie onlinelibrary.wiley.com/doi/10.1002/an… And ours in CHEM sciencedirect.com/science/articl…

Check out our recent paper on an enantioselective H atom transfer reaction catalyzed by an artificial metalloenzyme. A big thank you to Dongping and Xiang for this inspiring piece of work. nature.com/articles/s4155…

Understatement of the year...