This is inspiring.

Many cancers are metabolic disease complications

Bertero et al. link extracellular matrix stiffening of both cancer cells and carcinoma-associated fibroblasts to metabolic rewiring through a YAP/TAZ-dependent glutamate/aspartate crosstalk in the tumor niche. bit.ly/2HUvBlQ

Here’s a little video to welcome the Year of the Pig, with some tips on what to do should you encounter wild boars near the #NTUsg campus. Wishing everyone a Happy and boar-tiful Lunar New Year.

Smaller teams tend to produce new ideas and concepts, whereas larger teams tend to develop existing ones, according to an analysis of more than 65 million papers, patents and software products, published in Nature. go.nature.com/2EaMEML

AMPK can either inhibit or promote tumor growth depending on tumor type and context. Eichner et al. show that AMPK, unlike LKB1, has a pro-tumorigenic role in a Kras-dependent, non-small-cell lung cancer model. bit.ly/2Xottq9

What is interesting here is just how LITTLE genetic risk there is. 3x risk in top 5% explains virtually NONE of the population attributable risk for #T2D #diabetes (and its not lack of n responsible either)

goes well with running/jogging.

Keytruda saved Merck

A new #imaging method could be used during an operation to make #surgery more precise bit.ly/2tR3oCG | #breastcancer #ultrasound

7 Reasons You Should Run In a New City bit.ly/2TJWFK8

One of the most brilliant minds! and he lives in Singapore.

News & Views: A Nature paper reports that histones can also be modified by the addition of serotonin, a molecule with essential roles in regulating neuron activity. go.nature.com/2Hlu72S

The power of imaging in human studies

I suppose "too busy" is still a good reason not to run

Passing of Dr Sydney Brenner, Nobel Laureate, renowned pioneer in molecular biology, A*STAR Senior Fellow. a-star.edu.sg/News-and-Event… #scientists #research #science #biology #NobelPrize #physiology #Medicine

Announcing a new writing project today, called Heureka!, that explores stories of creativity, identifying methods to be more creative, and using heuristics to learn lessons of what others have already learned and discovered themselves. New articles at matthewhirschey.com

Using a multi-omic approach, Ericksen et al. find that loss of BCAA catabolism in carcinogenesis enhances mTORC1 activity and promotes tumor development and progression: bit.ly/2M7IJWX

Congratulations, Scott!

"I am convinced that if I had to spend less time on securing funding, I would be more productive and creative." goodscienceproject.org/articles/inter… @SudhofThomas