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Massively parallel mapping of substrate cleavage sites defines dipeptidyl peptidase four subsite cooperativity biorxiv.org/content/10.110…

In our new paper in Nature Communications (rdcu.be/drAkx) we show #robustness of pharynx-to-body #scaling to tissue-specific growth inhibition involving the mechanotransducer #YAP-1 rdcu.be/drAkx. 👇for 🧵. PhD positions available for follow-up (Pls RT). @IZB_unibern

Our paper is out today in nature! Imagine getting this plot when studying single-cell data of growing bacteria! Could it be the cell cycle?! We found that a gene’s response to its replication reveals gene regulation on a genomic scale. nature.com/articles/s4158… Andrew Pountain

We’re thrilled to report the discovery of ChAHP2! Its chromatin binding specificity is distinct from ChAHP, predominantly associating with ERV and LINE1 retrotransposons via HP1beta-mediated binding of H3K9me3. biorxiv.org/content/10.110…

Peters Lab: Excited to share our latest preprint lead by Greg Fanourgakis (Grigo Fanou). Key findings are that DNA methylation modulates nucleosome retention in sperm and H3K4 methylation deposition in early mouse embryos. biorxiv.org/content/10.110…

Congratulations Luke!

Ever wondered how biological clocks time developmental events? Grosshans Lab FMI science we do - and use experiments and theory to find out. Join us – FMI's PhD program is now accepting applications 👇, and we offer #phdpositions.

What are the forces shaping m6A evolution? Using interspecies hybrids in yeast and mammalian systems, we find that changes in m6A levels are nearly exclusively driven in cis. genomebiology.biomedcentral.com/articles/10.11…

What's better than publishing a paper? Publishing it next to another paper from your former postdoc's lab. Congratulations, Manuel de la Mata & Team! Full stories on how miRNAs get degraded at doi.org/10.1093/nar/gk… & doi.org/10.1093/nar/gk… Nucleic Acids Res FMI science

Preprint by Grosshans Lab (FMI science) & Ward Lab (UC Santa Cruz) w/ 1st authors Rebecca Spangler, @GuinevereAshley, Kathrin Braun "A conserved chronobiological complex times C. elegans development" bioRxiv doi.org/10.1101/2024.0…

Two more weeks to apply for #PhD position in #Quantitative #Developmental #Biology using #Celegans. Join us to study how growth signals control development and aging in space and time. GIF is shows bursts of FoxO/DAF-16 activity. ohws.prospective.ch/public/v1/jobs…

A novel protein complex, ChAHP2, is involved in silencing of ERVs and LINE1 elements, complementing the SINE-targeting ChAHP complex, to bring about efficient retrotransposon repression. Marc Bühler Josip Ahel Learn more here: ➡️ tinyurl.com/gd351769

Tissue-resident memory T cells break tolerance to renal autoantigens and orchestrate immune-mediated nephritis pubmed.ncbi.nlm.nih.gov/38961265/

Glad you are still here. Let others know and RT: x.com/betowbin/statu…

Excellent choice - congratulations, Victor and Gary, for this deserved recognition of your breakthrough work!

Welcome to Thomas Welte as a new Associate Member of the NCCR RNA & Disease! Clinician Scientist at University Hospital Freiburg and FMI science . Soon establishing a research lab on post-transcriptional gene regulation in organ development and repair at the UZH Science.

cell.com/developmental-…

Novel insights into the silencing of an understudied transposable element - check out our latest preprint by Jakob Schnabl-Baumgartner and colleagues bsky.app/profile/did:pl… biorxiv.org/content/10.110…