🎉 Our study of T cell responses during SARS-CoV-2 breakthrough infection is now available online Immunity! Check out the great tweetorial from Marios Koutsakos, and find the full paper below: cell.com/immunity/fullt…

Neutralizing #antibody titers elicited by either ancestral or bivalent #COVID19 #vaccine boosters are predicted to increase protection against severe disease due to #SARSCoV2 variants. Deborah Cromer Infection Analytics Program Kirby Institute, UNSW nature.com/articles/s4159…

🥳 So happy to share my first, first-coauthored paper is finally out! 🥳 What did we do! Well, we looked at 1) #antibody immunity to #SARSCoV2 variants after #vaccination and 2) natural ACE2 polymorphism on affinity to #RBD! A nice summary of key take homes linked below 🦠 1/2

Antibodies are sufficient for protection against #COVID19! Our new research in Nature Communications shows monoclonal antibodies can provide similar protection to vaccination. nature.com/articles/s4146… Infection Analytics Program Deborah Cromer Kirby Institute, UNSW UNSW Medicine & Health Stephen Kent

1) I feel this paper by Mattias Forsell's group is often overlooked but shows something very important: Binding antibody to SARS-CoV-2 spike - in the absence of strong neutralizing antibodies to a new variant - predict protection from mortality. thelancet.com/journals/lanep….

scientist after sequencing lots of single cells

A full analysis of the potential impact of the 34 mutations in the new #BA.2.86 #SARSCoV2 strain by Bloom Lab The number of spike mutations relative to BA.2 and XBB.1.5 is comparable to those in first #Omicron strains relative to Wuhan-Hu-1. slides.com/jbloom/new_2nd….

New study on imprinting against influenza B viruses – yeap they are still a thing! 🦠 TLDR: birth year = specific cross-reactivity and susceptibility to future IBV variants! Want to know more? Like Ariadne and Theseus, here’s a thread to help you out! 🧵

OUT NOW 📢 Immune imprinting in early life shapes cross-reactivity to influenza B virus haemagglutinin Marios Koutsakos @Viralvaxlab Doherty Institute nature.com/articles/s4156…

Great to see our FluB imprinting paper out in Nature Microbiology