🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Braunwald reverses 35 year old stance in asymptomatic severe aortic stenosis &AVR bit.ly/3EBr0Tt Don’t wait for symptoms to develop in severe AS! No more “watchful waiting” #justdoit Act & send patient for TAVR or SAVR JAMA Cardiology

🫀 A new clinical study in #CJC demonstrates that speckle tracking #echocardiography can detect myocardial strain abnormalities predicting heart failure in arrhythmogenic right ventricular #cardiomyopathy patients, aiding risk stratification and treatment decisions. Read more ⬇️

How should we interpret STICH in the REVIVED era? Did improving OMT between the trials move the goalposts? Can we compare CABG to PCI? The first IPD analysis of randomised data in ischaemic LVSD out today in EHJ Editor-in-Chief. academic.oup.com/eurheartj/adva…

#EditorsChoice Optimal Shunt Type for Norwood Procedure: Predicted Adverse Impact of Discordant Surgical Approach from Jef Van den Eynde, Manlhiot, and coauthors👇 doi.org/10.1016/j.atho… Xander Jacquemyn Shelby Kutty, MD, PhD, MHCM

🔥Hot off the press🔥 Read our study just published in JAHA showing that there are insufficient #RCT data on 🧠cerebral embolic protection device use to provide conclusive findings for stroke outcomes after #TAVI #TAVR ahajournals.org/doi/10.1161/JA… #StructuralHeart🫀 💥Nice

There are insufficient randomized controlled trial data on cerebral embolic protection device use to provide conclusive meta-analytic findings for stroke outcomes 🔗: pubmed.ncbi.nlm.nih.gov/40118799/ Ibrahim Sultan Derek Serna-Gallegos MD Michel Pompeu Sá Xander Jacquemyn UPMC Heart and Vascular Institute American Heart Association #TAVI

Maintaining radial patency after CABG Surgery: the Randomized ASRAB -Pilot Study. Lower graft failure with nicorandil or isosorbide mononitrate compared to diltiazem #AHAJournals ahajrnls.org/41XUiUu

Thrilled to share our review on clonal hematopoiesis (and CHIP) in cardiovascular diseases! Michael Honigberg, MD, MPP and I discuss CHIP's potential role as prognostic factor and therapeutic target in atherosclerotic disease, heart failure and arrhythmias nature.com/articles/s4156… Nature Reviews Cardiology

Many choices for trials to highlight the past week, but I love this one. Again from (where else) Copenhagen If I had a dollar for every time a sent a pt with heart failure for thoracentesis for pleural effusion Boom. No benefit in an RCT

🔥Hot off the press: early aortic valve replacement (AVR) in asymptomatic severe aortic stenosis significantly reduces all-cause & cardiovascular mortality, plus heart failure hospitalizations, our RCT meta-analysis shows. 📎doi.org/10.1016/j.ijca… 🌍 Great international effort!

🔥Hot off the press🔥 Read our study just published in International Journal of Cardiology about early #AorticValve replacement in asymptomatic severe #AorticStenosis internationaljournalofcardiology.com/article/S0167-… #StructuralHeart🫀 #SAVR #TAVR 💥Collaboration with Xander Jacquemyn #JeroenBax Mateo Marín-Cuartas #MichaelBorger

Early #AorticValveReplacement in pts w asymptomatic severe aortic stenosis is associated with ⬇️ all-cause mortality, CV mortality, HF hospitalization vs conservative management 🔗: pubmed.ncbi.nlm.nih.gov/40222660/ International Journal of Cardiology Xander Jacquemyn Michel Pompeu Sá Ibrahim Sultan UPMC Heart and Vascular Institute #AVR

A #SystematicReview demonstrates that while #TAVR explant is a rare event, its clinical impact is non-negligible 🔗: pubmed.ncbi.nlm.nih.gov/40270844/ Michel Pompeu Sá Ibrahim Sultan Xander Jacquemyn Danial Ahmad, MD, MPH Eishan Ashwat Derek Serna-Gallegos MD UPMC Heart and Vascular Institute

JUST OUT! U.S. FDA just approved Edwards Lifesciences Sapien 3 #TAVR for asymptomatic severe AS!!! businesswire.com/news/home/2025…

Dr. Gilbert Tang U.S. FDA Edwards Lifesciences Approval based on EARLY TAVR? So we are now pulling the trigger & starting the clock (for durability of a valve, for which we don’t have long term follow-up) in patients without symptoms, at a younger age, based on a trial whose interpretation is highly controversial? 🤔

#EHJCVI 🫀 What’s the hemodynamic impact of isolated ASD, isolated PAPVC, and combined ASD–PAPVC? 🧲 This CMR study found no anatomical influences, outcomes appear mainly driven by the degree of shunting 🔁 Want to know more? 👉 doi.org/10.1093/ehjci/…

Meta-analysis demonstrates no statistically significant difference in all-cause death after TAVI with self-expandable valves vs balloon-expandable valves 🔗: pubmed.ncbi.nlm.nih.gov/40414661/ Xander Jacquemyn Derek Serna-Gallegos MD Ibrahim Sultan UPMC Heart and Vascular Institute Michel Pompeu Sá #TAVR #TAVI

We have officially opened our Editorial Fellowship applications for 2025-2026! The deadline is June 30, so apply now! More information here: nature.com/npjdigitalmed/…

🔥Hot off the press in JACC Journals: In pediatric HCM, myocardial work (MW) declines over time and is linked to adverse outcomes. MW adds prognostic insight, but doesn’t outperform GLS (yet). 🔗: doi.org/10.1016/j.jaca… Thanks to all co-authors! 🙏 #CardioTwitter #HCM

Less-Is-More Cardiologist Victor Dayan Here is another egregious example of counting ‘crossover’ as a component of composite outcome (TRILUMINATE-Pivotal)