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Our latest is out!! 🙌Active shape programming drives Drosophila wing disc eversion | Science Advances science.org/doi/10.1126/sc… Physics of Life Dresden MPI-CBG Dresden MPI-PKS Dresden Center for Systems Biology Dresden @_JFuhrmann_ abhijeetkrishna Marko Popovic Carl D Modes 🧵

Hi, I’m David Brückner David Brückner. I’ll take you through how cells in a tissue can use information distributed by biochemical gradients to make decisions, and how we can measure such positional information. x.com/EpiMechFC/stat…

📢Paper alert📢 Great 3D Matter Made to Order collaboration with the group of Eva Blasco on stimuli-responsive mechanical metamaterial now out in Science Advances. With Li-Yun Hsu, Clara Vazquez-Martel, Christoph A. Spiegel and X-less Santiago Gomez Melo and Falko Ziebert. Here a 🧵1/n

Finally, out in nature! A great team effort to address very constructive reviews. With Paolo Caldarelli, Alexander Chamolly, @villedieuA_bio, Olinda Alegria, Carole Phan, and Francis Corson , with the support of European Research Council (ERC) . rdcu.be/dTFJV

We wrote a fun review all about the different types of mechanosensing and the ways cells regulate these important processes. Check it out!

Thrilled to share that our paper on 3D traction force measurements of migrating immune cells (and growing axon growth cones) is now published in Nature Physics: rdcu.be/dU9Nj. Huge thanks to everyone who worked so hard to make this happen!

1/4 In our new concept paper in Biological Theory, we elaborate an investigative approach that prioritizes the art of careful observation, the biological whole, and physical thinking in order to develop novel biological theories of morphogenesis. link.springer.com/article/10.100…

Very nice focus issue Current Biology on Physics and Biology. cell.com/current-biolog… Some of us wrote a perspective article on "Where physics and biology meet" led by Wallace Marshall and Deborah Taylor. cell.com/current-biolog…

Sad to witness the implosion of #scitwitter, with all the great moments it brough us, but scientific exchange seems to be shifting for good.

New preprint from the lab! We studied how single cells migrate up, down and about fibronectin gradients. Experiments by Isabela Corina Fortunato, PhD , theory by David Bruckner. Collaboration with Edouard Hannezo and Raimon Sunyer IBEC biorxiv.org/content/10.110…

Explore emerging research with field leaders Keystone Symposia - Organoids: Engineering Innovative Approaches for Basic and Translational Insight. May 11-14 in Whistler, Canada! keysym.us/KSOrganoids #KSOrganoids

1/7: New paper alert! Excited to share our co-first author paper on Micro Immune Response On-chip (MIRO) a model that recreates the tumour-stroma interface for immunotherapy testing! Oriol Mañé Benach and I wrote this thread to break it down for you. 👇🧵 More: shorturl.at/evTKS

(6/6) In summary, our new pipeline now allows us to dissect how such a complex multicellular system like a budding intestinal organoid achieves its mechanical stability. Congrats to our shared first authors Oliver and Kim for this amazing work biorxiv.org/content/10.110…

There’s tons out there about fibroblast #mechanobiology in disease. In Confinement Mechanobiology Lab at MBI’s new review in APL Bioengineering, Yeji gives you the who/what/where/when/how/why of mechanosensitive fibroblast activation, from CAFs to FAFs and nearly everything in between! pubs.aip.org/aip/apb/articl…

How to turn a layer of fibroblasts into a tulip 🌷? Check out our new pre-print on shape-programmable living surfaces. Led by Pau Guillamat IBEC biorxiv.org/content/10.110…

🚨 Second preprint of the week! We uncover the multiscale dynamics of active viscoelastic buckling in epithelia. We harness these mechanical instabilities for synthetic morphogenesis. Led by Nimesh Chahare🙌. Theory by Marino Arroyo and team. biorxiv.org/content/10.110…

A thread of our new preprint 🧵👇 🤩