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Register today, save $100 and join Cell Symposia #CSStructuralBiology23 organizers Zihe Rao Tsinghua University, ShanghaiTech University @NKU1919, Xiangxi Wang, Institute of Biophysics, CAS, Karin Kühnel Structure & Jia Cheng Cell in China, November 2023. hubs.li/Q01ZMtBj0

We are thrilled to share our recent study in collaboration with the Olson lab Eric N. Olson on the mechanism behind myoblast fusion. It was a wonderful experience to work with both teams! nature.com/articles/s4159…

Check out this interesting model for assymetric gating in heteromeric ligand gates ion channels. Congratulation to Xiaofen Liu for this exciting work! rdcu.be/dokrF

Excited to share our new paper! CryoEM, Protein ID, and AlphaFold reveal how an ER chaperon facilitates Wnt production. We also show how lipids control Wnt release and how RECK binds Wnt7 to trigger its specific signaling. Thanks to Nadia Elghobashi-Meinhardt! authors.elsevier.com/a/1hxN2L7PXmd-7

Now online! Molecular basis of Wnt biogenesis, secretion, and Wnt7-specific signaling dlvr.it/Sxcb27

Our work on the human neuronal vesicular monoamine transporter VMAT2 in online nature. This work was led by talented scientists Shabareesh Pidathala and Yaxin Dai Y. Dai, in a wonderful collaboration with Zhe Zhang's lab. nature.com/articles/s4158…

Here we determined the cryo-EM structure of TMEM63C, and confirmed its predominant monomeric state and the significance of TM0-TM6 coupling in channel activity. | Cryo-EM structure of TMEM63C suggests it functions as a monomer | Nature Communications. nature.com/articles/s4146…

In the latest issue! Molecular basis of Wnt biogenesis, secretion, and Wnt7-specific signaling dlvr.it/Syg1m1

Duojia Pan, Ph.D., Chair of Physiology, has advanced the study of the Hippo signaling pathway, vital in tissue growth across species. His contributions have garnered considerable acclaim. Explore his pioneering research and impactful medical career. bit.ly/3RPiovy

In collaboration with Yufeng Wang Group at HKU , we have developed a method that offers an alternative strategy to optimize cryo-sample preparation. This method involves protecting particles from AWIs by simply incubating them with MSBP.

So glad to share our preprint: CLSTN3B enhances adipocyte lipid droplet structure and function via endoplasmic reticulum contact biorxiv.org/content/10.110…

We are so proud to have manufactured the tweezers that made this work possible. Amazing work from a brilliant scientist. Great job Yasu!!

Happy to share our new work just came out in Cell Research! We discovered Mfsd7c as a choline transporter and showed that excess choline is exported out from the brain! This is an unexpected finding. Science is wild! nature.com/articles/s4142…

New work from SHUBHAM SINGH on the mechanism of lysosomal #lipid degradation and its link to neuronal health HHMI Tobias Walther, 華濤北 @BobFarese SKI_CellBio #CellBiology #neuro #Alzheimers

Structural mechanism of bacteriophage lambda tail’s interaction with the bacterial receptor. Nat Commun doi.org/10.1038/s41467…

We are thrilled to share our recent study on the lysosomal transporter Sialin uncovering its role in sialic acid and neurotransmitter transport. Thanks to Chia-Hsueh Lee Nadia Elghobashi-Meinhardt for their contribution. rdcu.be/dIMXy

Now online! Molecular insights into human phosphatidylserine synthase 1 reveal its inhibition promotes LDL uptake dlvr.it/TCcP6y

Available online - the Forum "Clues into Wnt cell surface #signalosomes and its biogenesis" from Philip Schmiege and Xiaochun Li. #WntSignaling #WntBiogenesis #WntProduction authors.elsevier.com/a/1jzmb_M0e493…