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INTEDE: interactome of drug-metabolizing enzymes academic.oup.com/nar/advance-ar…

One nice paper: INTEDE: interactome of drug-metabolizing enzymes pubmed.ncbi.nlm.nih.gov/33045737/

Nice paper x.com/natureprotocol…

RESEARCH | From the Auwerx Lab (@epfl_en): Genetic variants of the #mitochondria supercomplex assembly factor COX7A2L that promote cardiorespiratory #fitness are identified in the skeletal muscle of mice & humans. nature.com/articles/s4225…

Latest preprint from our lab (Auwerx Lab), where Xiaoxu Li uncovers genetic and dietary modulators of IBD risk using the BXD family of mice.

Our work at Auwerx Lab on #IBD risk is now published in eLife - the journal. Congrats to Xiaoxu Li and coauthors! doi.org/10.7554/eLife.…

Congrats to Xiaoxu Li and our team who pinpointed candidate genes for #IBD risk using a combination of mouse systems genetics (BXD) and genetic epidemiology in humans (UK Biobank). eLife - the journal paper: elifesciences.org/reviewed-prepr… Press release: elifesciences.org/for-the-press/…

Sign up for the 3rd Dutch Translational Metabolism Conference! Keynotes include Luke O’Neill, Maria Falkenberg, Javier Gonzalez, Bart Deplancke, and Christiane Opitz!

The SNSF congratulates Anna Fontcuberta i Morral on her appointment as EPFL President. She is a professor of material science and she has held numerous roles at the SNSF. Currently she is a member of the Presiding Board of the National Research Council. sohub.io/ip9m

The work of Xiaoxu Li and collaborators defines a simple continuous and composite trait, termed the metabolic health score, that is more accurate in defining metabolic homeostasis and predicting future disease incidence sciencedirect.com/science/articl…

🧬🔬Our researchers at EPFL Life Sciences developed a metabolic health score using diverse mice strains, uncovering key genetic factors influencing metabolic health. Validated in human data, this study paves the way for personalized MetS treatments. go.epfl.ch/0b3455

Li et al. derive a continuous biomarker for metabolic homeostasis, the Metabolic Health Score (MHS), which they find associated with 2 genetic loci in BXD mice, and identify TNKS and MCPH1 as modulators of MHS in human datasets Xiaoxu Li Auwerx Lab cell.com/cell-systems/f…

High-content phenotypic analysis of a C. elegans recombinant inbred population identifies genetic and molecular regulators of lifespan dlvr.it/TF4qn8

Congrats to Yasmine Liu & team for demonstrating ACMSD inhibition reduces liver inflammation and early fibrosis in MASLD! Boosting NAD+ and reducing DNA damage in the liver are key to its effects. Paper, journal-of-hepatology.eu/article/S0168-…