
Xiaoyi Li
@xiaoyili10
BS @Tsinghua_Uni, PhD with @aventura71 @MSKCancerCenter, Postdoc with @JShendure @uwgenome
ID: 3372670786
12-07-2015 17:42:25
84 Tweet
296 Followers
526 Following

Excited to share our new work!!🥳How do cells lose totipotency to fate segregation? w Zernicka-Goetz Lab we found that early blastomeres experience a "Composite State" by displaying dual-lineages signatures! Link for full text👉: rdcu.be/dITfo


Very happy to share our latest w/ Devin Schweppe and Nobu Hamazaki labs, where we map the temporal dynamics and proteomic landscape of mammalian gastruloids. Sneek Peak 🧵below #stembryo #gastruloid #proteomics biorxiv.org/content/10.110…


7 years ago, I met a junior fellow named Jason Buenrostro who blew me away with a vision of futuristic genomic technologies Today, we (Ajay Labade, @carolinecomenho) are excited to share our first steps into that future: Expansion in situ genome sequencing 1/



Genome engineering excelled at small nucleotide changes, but large edits remained challenging. Recent innovations are changing this. We reviewed the field of structural variant engineering Nature Genetics 🧬 Juliane Weller Thomas Vanderstichele @LeopoldParts nature.com/articles/s4158…



Now out in Science Magazine we present 'Genome-shuffle-seq': a method to shuffle mammalian genomes and characterize the impact of structural variants (SVs) with single-cell resolution in one experiment. science.org/doi/10.1126/sc…

I’m delighted to share our work on scrambling the human genome using prime editing, repetitive elements, and recombinases Science Magazine! Raphael Ferreira @LeopoldParts Tom Ellis, george church @SangerInstitute science.org/doi/10.1126/sc… Lots of changes from the preprint. A🧵
