Ximena Jordan Bruno
@ximejordan
Nicos mom, relentless Hematologist, @UCCoficial,@Udelaruy @UVMVermont alumna.Learning from patients with leukemia and BM failure. Genetic risk enthusiast
ID: 158921906
24-06-2010 00:48:49
9,9K Tweet
2,2K Followers
5,5K Following
Welcome to the new era of 🧬 editing to cure leukemia- Remission of TP53-Mutant AML After HCT With Trem-Cel, a CRISPR/Cas9 Gene-Edited Allograft Lacking CD33, Followed by a Donor-Derived Anti-CD33 CAR T (VCAR33) JCO Precision Oncology ascopubs.org/doi/full/10.12…
New study of 90K exomes reveals population-based prevalence, penetrance, and clinical impact of MDS- and CHIP-associated gene variants—including novel germline RUNX1 mutations. Findings support early monitoring. #Genomics #MDS #CHIP #HemeOnc doi.org/10.1002/ajh.70… Iman Sarami, MD
Airborne pollutants are elevated in the Bronx, New York and correlate with worse #MDS outcomes. Exposure to similar pollutants leads to inflammation in vivo. doi.org/10.1002/ajh.70… Megha Verma @montefiorenyc @einsteinmed Aditi Shastri, MD
🧵Just out in Blood Blood Journals Portfolio: Rapid clonal selection within early hematopoietic cell compartments presages outcome to ivosidenib combination therapy ashpublications.org/blood/article-… We study how resistance and durable remission emerge in IDH1-mutant AML.
“I had hemophilia for nearly five decades. I went to Philadelphia and had a 45-minute infusion, and my hemophilia was gone.” Genes-> Medicine Nature Medicine nature.com/articles/s4159…
American Journal of Hematology | Blood Research Journal | Wiley Online Library🩸 #AML #leusm doi.org/10.1002/ajh.70… Benlazar S M A
Exercise as anti-cancer medicine (“Exercizumab”) Cancer Cell cell.com/cancer-cell/fu… Journal of Clinical Oncology ascopubs.org/doi/10.1200/JC…