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Very proud to announce the publication of CoBRA. The CFCE built this tool for reproducible analysis of our epigenetic data. Great work from Xintao Qiu and all our co-authors! #snakemake #epigenetics #reproducibleresearch sciencedirect.com/science/articl…

The new CFCE website has a great overview of our research, the Center staff, and some of our fantastic collaborations! Check it our here: cfce.dana-farber.org

Read our latest research "MYC drives aggressive prostate cancer by disrupting transcriptional pause release at androgen receptor targets". Great collaboration with David P. Labbé, PhD featuring Xintao, Nadia Boufaied and many other colleagues. rdcu.be/cNtZA

Thrilled to share our study published Nature Communications, which found that #MYC drives aggressive #prostatecancer by disrupting transcriptional pause release at #AR targets. Co-first authors Xintao and Nadia Boufaied. Co-lead Henry W Long + 31 co-authors! rdcu.be/cNtZA (1/15)

Congratulations Xintao CFCE-DFCI on having this published online JCI insight- Response to supraphysiological testosterone is predicted by a distinct androgen receptor cistrome insight.jci.org/articles/view/…

Our new paper "Response to supraphysiological testosterone is predicted by a distinct androgen receptor cistrome" is out in JCI insight. Wonderful collaboration with Eva Corey UW Urology Fred Hutch Cancer Center David P. Labbé, PhD and Matt Freedman lab. insight.jci.org/articles/view/…

We are happy to present our new method T1K to genotype highly polymorphic genes (KIR, HLA, ...) from RNA-seq/WGS/WES data. I'm grateful for the kind mentoring from Heng Li Bo Li Xiaole Shirley Liu and the hard work of Gali Bai. The preprint is available at biorxiv.org/content/10.110…

Working with scATAC-seq data? Having difficulty assigning clusters to specific celltypes? Introducing scATAnno, a python-based workflow annotating scATAC-seq data using reference atlases. Great work, especially Yijia Jiang, Zhirui Hu and Xintao Qiu! tinyurl.com/3tjmdb4w

New insights into HER2-negative breast cancer! 🧬 Our study identifies a unique subgroup with 17q12 deletion and heterozygous ERBB2 loss, linked to low HER2 expression and poorer overall survival. Dive into the full study here: sciencedirect.com/science/articl… #BreastCancer #HER2Negative