What happens when Xist is deleted in B cells in female mice? Turns out aged female mice develop lupus-like disease! Check out the latest preprint from the Anguera lab, led by fabulous Claudia Lovell ! biorxiv.org/content/10.110…

Job Alert!! The UPenn Center for Women's Health and Reproductive Medicine is hiring tenure track Assistant Professors, with a special interest in endometrial biology, gyn cancers, pregnancy and reproductive processes. Apply soon: apply.interfolio.com/153614

Xciting news + Jobs alert! 🚨 After wonderful years at Centre for Genomic Regulation (CRG), we are relocating beginning 2025 to CHU Sainte-Justine at Université de Montréal. If you want to be part of @payerlab 2.0, come and join us! We are hiring at all levels – see job ads in the thread 🧵below. 👇 1/5

BREAKING NEWS The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.

📣New paper alert from the lab! Lab alumni Isabel, Natalie Toothacre, Claudia Lovell from CAMB Graduate Group together with Penn Epigenetics faculty Eric Joyce @creminsLab investigate 3D ultrastructure of the inactive X in B cells. cell.com/cell-reports/f…

Jpx flips a bistable switch and reprograms the X-inactivation center in 3D by regulating CTCF loop formation. sciencedirect.com/science/articl… Congrats to Hyun Jung Oh, with team members Priyojit Das, Roy Blum, Andrea Kriz, Hun-goo Lee, and Yong-woo Lee!

An evolving landscape of PRC2–RNA interactions in chromatin regulation, by Aguilar Rodrigo Aguilar, Rosenberg, et al. now in print! Learn the latest about how Polycomb works with RNA in epigenetic regulation: nature.com/articles/s4158…