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"The big keratin eater" - Occasionally, the only clue to cystic met of a SQCC (especially in a neck node) would be the presence of multinucleated histiocytes with engulfed keratinized cell fragments. (The latter would not be seen in a branchial cleft cyst - the major DD).

Polypoid High-grade Dysplasia / Intracholecystic Papillary Neoplasm (ICPN) of the #Gallbladder with mixed cell lineage to include both gastric and pyloric as well as scattered goblet cells. The majority of these neoplasms harbor high-grade dysplasia. #GIPath #Pathology

Rectal mass - diagnosis? #GIpath #pathology

34th Brazilian Congress of Pathology meeting in Belem! Great morning session on transplant pathology!

We were thrilled to host Sarah Bean, MD, FCAP, @DrSMBean, Prof., DukePathDept, for our 2024 C. Bruce Alexander Lecture. Drs. Bean and Alexander are pictured with CristinaMagiGalluzzi, Chair, C. Bruce Alexander Endowed Professor, and current/former residents. bit.ly/3Ko3OYE

🚨 The FDA's proposed rule on #LDTs (Laboratory Developed Tests) could drastically impact patient care by limiting access to essential diagnostic tests! Timely editorial by Dr. Genzen and Dr. Moser in Lab Medicine #HealthcareReform #Pathology #LDTs" bit.ly/4bZtoPs

#GIPath #Pedipath #Hemepath Child with nausea, abdominal pain bx from the esophagus showing this isolated finding I still can not let this go 😅 What is the relevance of this isolated finding What would you say in the report, if you said 🤔 Chandra Krishnan, MD stephen lagana

#hemepath intestinal spirochetosis (r is spirochete stain), but...

Pancreatic Acinar Cells (PAS stain) ~ #histology #pathology #histoart #pathart

All you need to know about hepatoid carcinomas. An editorial and a new study uncover NTRK alterations in hepatoid carcinomas and adenocarcinomas with enteroblastic differentiation. 📖🔬 Don't miss our latest insights! 🚀🧬jcp.bmj.com/content/early/… jcp.bmj.com/content/early/…

#GIPath

Pancreatic neuroendocrine tumor (PanNET), WHO grade 1, 2.3 cm, ATRX mutant (& alternative lengthening of telomeres [ALT]). ALT-pos. NETs often have venous invasion (w/ tumor thrombi), leading to metastases #Pancreas #NET #PancreaticCancer #NeuroendocrineTumor #GIPath #Pathology

Ischaemic small bowel with an unexpected finding! #PathTwitter #GIPath

Small focus in prostate biopsy. Focal cancer vs something else? 😉 #GUpath

Intraductal Oncocytic Papillary Neoplasm (IOPN), #HGD, of the main & branch ducts in the #Pancreas. Interesting story, FNA in 2010 when 1.8 cm & repeat testing found a PRKACA fusion. The patient was asked to f/u & now 6.0 cm. #Pathology #GIPath #PancreaticCancer #PancreaticCyst

Pancreatic “Acinar Cell Carcinoma” will often display syncytium of cells with nuclei containing macronucleoli on FNA.

This unusual-appearing pancreatic ductal adenocarcinoma has a clear cell phenotype; we considered spread from a renal cell carcinoma and found loss of DPC4/SMAD4 helpful, as noted years ago. PMID: 10623651; PMCID: PMC1868651.

Unusual appearance of mucinous adenocarcinoma of lung with a large glandular structure almost completely surrounding an arteriole. I think that this glandular structure is likely within a lymphatic. Opinions? #pulmpath

A tip for PhD students