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#cshlcrispr24 If you are interested in gene regulation/joining the lab, I am happy to chat!

🎇🎄Some holiday reading: Overdue TWEETORIAL on the latest preprint from our lab. 🎇🎄 In this work, superstar postdoc Xinhe Xue combined 2 kinds of pooled CRISPR screens to pinpoint noncoding regulatory elements and the transcription factors that activate these elements.

Excited to share my latest preprint on establishing a generalizable toolkit for decoding the gene regulatory landscape using two types of CRISPR screens. Big thanks to my amazing mentor Neville Sanjana for the in-depth thread below. Looking forward to feedback and comments!

I’m delighted to share our work on scrambling the human genome using prime editing, repetitive elements, and recombinases Science Magazine! Raphael Ferreira @LeopoldParts Tom Ellis, george church @SangerInstitute science.org/doi/10.1126/sc… Lots of changes from the preprint. A🧵

🚨📰TWEETORIAL time📰🚨 Excited to share recent work from our lab on noncoding genomics 🔎🧬: High-resolution CRISPR mutagenesis of the MYC TAD (~3 Mb) in 6 different human cancer cell lines nature.com/articles/s4146…