A DGCR8/FLII/JUN-mediated transient transcriptional activation governing embryonic morphogenesis and pluripotency transition during implantation. #PKUResearch cell.com/molecular-cell…

Dr. Di Zhang and collaborators uncovers L-lactylation of lysine as the predominant lactylation isomer in cellular histones, which dynamically responds to glycolysis and correlates positively with lactyl-CoA levels. #PKUResearch nature.com/articles/s4158…

Carolyn Rasmussen nominated for shaping the field of plant biology insideucr.ucr.edu/awards/2024/07… #UCRscience #plantbiology #plantcells #plantresearch #womeninscience #ASPB #ucr #ucriverside

Groups of Professor Qing Li from Peking University and Danesh Moazed from Harvard reveal mechanisms of epigenetic memory through parental histone recycling A replisome-associated histone H3-H4 chaperone required for epigenetic inheritance: Cell cell.com/cell/fulltext/…

Proteasome resides in and dismantles plant heat stress granules constitutively: Molecular Cell cell.com/molecular-cell… Wei Wang's lab at Peking University revealed a role of the proteasome in the regulation of stress granule dynamics

Deng, M., Du, S., Hou, H. et al. Structural insights into the high-affinity IgE receptor FcεRI complex. Nature (2024). doi.org/10.1038/s41586… Junyu Xiao's lab at Peking University revealed the structure of a receptor of IgE, which causes allergies.

Dr. Ying Zhang and collaborators found that early tumor editing preferentially suppresses innate immune signaling to reduce tumor immunogenicity, which can be reversed by inhibiting DNA methylation. #PKUResearch nature.com/articles/s4159…

Proteasomes regulate stress granules (SG) dynamics and confer plant heat stress resistance by promoting SG clearance without affecting SG components’ mobility. #PKUResearch cell.com/molecular-cell…

m6A-modified cenRNA stabilizes CENPA to ensure centromere integrity in cancer cells: Cell cell.com/cell/fulltext/…

m6A-modified cenRNA stabilizes CENPA to ensure centromere integrity in cancer cells: Cell cell.com/cell/fulltext/… Jun Liu's group at Peking University shows that the famous CENPA protein is actually a "reader" of m6A modification in RNA

The identified functional map of serine, threonine and tyrosine residues is highly relevant to phosphorylation, structural maintenance and clinical significance. #PKUResearch nature.com/articles/s4158…

Reversal of diabetes in a T1D patient using chemically-induced pluripotent stem cell-derived islets and a novel transplantation strategy. #PKUResearch cell.com/cell/fulltext/…

Research from Junyu Xiao's lab unveils the cryo-EM structure of human IgM with CD5L! They show that CD5L reduces IgM's binding to pIgR while preserving FcμR binding and complement activation. An updated perspective on circulating IgM! #PKUResearch nature.com/articles/s4146…

A fast chemical reprogramming system to generate human pluripotent stem cells was developed, providing an innovative strategy for stem cell manufacturing. #PKUResearch nature.com/articles/s4158…

Zhe Zhang and Pengli Zheng's labs have uncovered the molecular basis of VANGL-PK interaction, advancing future research on the planar cell polarity pathway. #PKUResearch nature.com/articles/s4146…

Almost all neurons co-release peptides and small transmitters. Yulong Li Lab Latest research where new GRAB sensor promotes better understanding of the dynamics and molecular regulation between neuropeptide and neurotransmitter release in vivo. #PKUResearch

A study reports optimized mitochondrial base editors with reduced off-target effects to facilitate the generation of mouse models of human mitochondrial diseases. #PKUResearch nature.com/articles/s4158…

Dr. Jackson Champer's team generated sterile Anopheles stephensi using a gene drive system targeting dsx, aiming to eliminate vectors and stop malaria. #PKUResearch nature.com/articles/s4146…

A clearer view of membrane protein biogenesis in action!  Unlocking the mysteries of how proteins move into biological membranes. #PKUResearch cell.com/cell/fulltext/…

We are ready to recruit new postdocs to join our team at MPI Biology Tübingen! Please help us spread the words. Thank you!!! 😊