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My lab and I have been thrilled to work with Prof. Akiko Iwasaki and her lab on this project. This is our first debut into systems immunology using a new platform we developed called REAP. We'll have a lot more to say about REAP soon, but please check out Akiko's 🔥 Tweetorial below

HELLO world! I'm pleased to announce that our paper investigating the role of tumor neoantigens in driving responses by TFH cells is out in biorxiv. This is a collaboration with Joe Craft and is the brilliant work of @cancuiyale. Tweetorial to follow.

Check it out here👀Dr. Craig Wilen Craig Wilen #Genome-wide #CRISPR screens reveal host factors critical for #SARSCoV2 infection. bit.ly/2LvgbGS #research #COVID19 Yale Department of Immunobiology Cell Press

Thanks, Immunoglitch, for highlighting our 'Deficiency in ADA2' (DADA2) report J Clinical Immunolog led by Joel Brooks and Andrew Rice Yale Department of Immunobiology. Many thanks also to collaborators Drs. Saquib Lakhani, Elif Dokmeci, Amy Cruickshank, Michael Hershfield, Jasmeen Dara, and others.

What is the relevance of viral load in #COVID19 disease severity? A very talented Yale MSTP student Julio Silva found that saliva viral load to be a better predictor of disease than nasopharyngeal viral load. Here is a thread to explain the findings. (1/n) medrxiv.org/content/10.110…

Using both mouse and human brain tissue, researchers at Yale School of Medicine have discovered that #SARSCoV2 can directly infect the central nervous system and have begun to unravel some of the virus’s effects on brain cells (bit.ly/38BjLbA). Press release: bit.ly/3qbXrLD

Neurological symptoms are frequently observed in #COVID19. Using three independent approaches - mouse model, human brain organoid and autopsies of COVID-19 patients, eric hoyeon song @virusesimmunity team demonstrates evidence of #SARSCoV2 neuroinvasion. bit.ly/38BjLbA

This new Journal of Experimental Medicine paper supports #SARSCoV2 attack on brain cells via brain organoids, mouse models, and patient autopsy. Yale University Yale Lab Medicine Yale Department of Immunobiology Craig Wilen eric hoyeon song Prof. Akiko Iwasaki Eric Topol

Excited to share our new paper led by Jennifer Chen looking at the role of NSAIDs in #COVID19. NSAIDs dampen the cytokine and antibody response to SARS-CoV-2 infection ASM JVirology Editors Yale Lab Medicine Stephanie Eisenbarth Yale Department of Immunobiology 1/n jvi.asm.org/content/early/…

Congratulations to Stephanie Eisenbarth for being named in top 100 Women in Food Allergies bit.ly/39OGy38 Yale Lab Medicine Yale Department of Immunobiology Yale School of Medicine Yale University

#Neurological symptoms are frequently observed in #COVID19. Using 3 approaches - mouse model, human brain #organoids & autopsies of COVID-19 patients, Song eric hoyeon song, Iwasaki @virusesimmunity and colleagues demonstrate evidence of #SARSCoV2 neuroinvasion bit.ly/38BjLbA

There is so much misinformation and fear-mongering around #COVID19 vaccines for pregnant and nursing women. A brilliant Yale MSTP student Alice Lü-Culligan, MD, PhD and I wrote this OpEd to dispel these myths, and provide relevant facts. Please share widely. nytimes.com/2021/01/26/opi…

Since the pandemic began, Prof. Akiko Iwasaki and her team have learned a lot about immunity to the virus by studying sex differences. “Age and sex are where immunological changes intersect,” she says. news.yale.edu/2021/01/25/sci…

Low et al show memory T cells in different anatomical locations have unique reactivation mechanics & antigen-presenting cell requirements that drive qualitatively distinct recall responses bit.ly/2UMajLw From The Year in Experimental Medicine: bit.ly/3p0REsb

I’m excited to announce that our paper showing how tumor draining lymph nodes contain a long-term, stable reservoir of anti-tumor CD8 T cells is now online at biorxiv. This is the beautiful work of Kelli Anne, a postdoc in the lab. Tweetorial:

Seeking candidates for TWO tenure-track assistant/associate positions for Yale Department of Immunobiology: one for Section of Human & Translational Immunology and the other one for general immunology. We welcome applicants from diverse backgrounds. Please apply & RT 😊 apply.interfolio.com/99554

We are a super collaborative/supportive/fun group with awesome colleagues like Ye Grace Chen Carrie Lucas Nik Joshi @Aaronmring Craig Wilen Ellen Foxman Jeffrey Ishizuka Steven Kleinstein 🖥 @OConnorLabYale Vishwa Deep Dixit Marcus Bosenberg Ruslan Medzhitov Richard Flavell & many more! Join us!

We are delighted to announce that Yale Department of Immunobiology is looking to recruit two new faculty colleagues at the assistant/associate professor level, with one in the department’s Section of Human and Translational Immunology. Please apply and RT! apply.interfolio.com/99554.

Thank you, Jenny. I thoroughly enjoyed teaming up with the talented Stephen Lanahan and our University of Basel colleague Dr. Matthias Wymann on this PI3K-gamma review Nature Rev Immunol.

Yale’s first annual 🧬 Day of Immunology 🦠was today!! Yale Department of Immunobiology #gradstudents and #postdocs introduced 60+ newhavenpublicschools students to #vaccines, #allergies and more! Thank you Yale Pathways to Science for your support! onha.yale.edu/event/day-immu… #STEM #outreach