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Cancer immune evasion, immunoediting and intratumour heterogeneity go.nature.com/3BPBMoc

Immunogenicity cell death (ICD) is a general term to define the functional results from a cytotoxic treatment. There is still need for decisive molecular mechanisms to set up its role as a “subtype” of cell death. From the therapeutic point of view, it is enough.

Camouflage, coercion and cytoprotection are the new 3C paradigm for cancer cell immune evasion. By giving definition, intervention can be investigated deeper.

🍷Intracellular domain (ICD) of PD-1, the ITIM and PRS regions-> crucial for recruiting Shp2, with mutations in these regions significantly weakening the interaction. 🍷Human PD-1 has a stronger binding affinity to Shp2, providing insights into PD-1 signaling mechanism.

CXCL9 and CXCL10 bring the heat to tumors | Science Immunology science.org/doi/10.1126/sc…

Results from our phase II trial of brain MRI surveillance in stage IV breast cancer now out in SNO academic.oup.com/neuro-oncology… By 6 months, about 25% of patients developed brain mets regardless of subtype OncoAlert Thank you Florida Breast Cancer Foundation for the support!

We are excited to announce the release of the enGenome VarChat track for hg38 and hg19. This track uses AI to search papers for variants, providing information such as its gene, HGVS nomenclature, and dbSNP rsID. Learn more at genome.ucsc.edu/goldenPath/new….

I guess mitochondria is the Sauron of the cell. Where is the ring?

Microsoft open-sourced a no-code data analysis tool! Introducing Data Formulator, an LLM-powered, no-code tool that transforms data in a snap and creates stunning visualizations using AI. 100% open source

My thoughts on organ preservation for esophagus/GEJ – pros & cons, & key questions. SANO helps to address several points.

Navigating established and emerging biomarkers for immune checkpoint inhibitor therapy cell.com/cancer-cell/ab…

gganimate is a powerful extension for ggplot2 that transforms static visualizations into dynamic animations. By adding a time dimension, it allows you to illustrate trends, changes, and patterns in your data more effectively. Whether you're exploring time-series data or

Popular methods like UMAP & t-SNE are stochastic and distort data structure. Bonsai - a novel method - builds trees to relate high-dimensional objects, accounting for measurement noise. biorxiv.org/content/10.110…

How to select pts with HCC for various local therapies? RFA ,MWA , TACE , SIRT , SBRT . Useful for clinical decision-making. Taken from #asco25 ASCO Do u agree ? Yakup Ergün Dr. Nina Niu Sanford Jeff Ryckman OncoAlert Kate Sears

Thrilled to share scverse x Biomni! Biomni agent now supports 10 scverse core packages including scanpy, squidpy, scirpy, pertpy, etc! You can now use natural language to unlock complex single cell, spatial, and perturbation data analysis to generate novel