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Introducing our new study @ Tissue-PPT, an Extensive Atlas of Proteome and Phosphoproteome Turnover across mouse tissues and brain regions. biorxiv.org/content/10.110… Yansheng Liu Junmin Peng Eugenio F. Fornasiero #Proteomics #TeamMassSpec #Proteinturnover

“Integrated multimodal cell atlas of Alzheimer’s disease” by Gabitto, M. I et al. Nature Neuroscience nature.com/articles/s4159…

Our new preprint is up on #biorxiv! We uncovered shared #Alzheimers pathways in human and mouse proteomes and demonstrate ways amyloid affects protein turnover in the brain. biorxiv.org/content/10.110… #AlzheimersResearch #proteomics #omics #Neuroscience #Proteinturnover #MassSpec

Microglial lysosomes may be a crucial incubator for amyloidosis. There, ApoE and Aβ co-aggregate, forming seeds of Aβ plaques. @DZNE_en ow.ly/wGET50TWHtC

Now online! Decreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and its lipid cargoes in lysosomes dlvr.it/TG76l2

Integration of CSF proteomics, metabolomics and genetics identify causal and druggable targets for #Alzheimers disease The Cruchaga lab published two side-to-side manuscripts in Nature genetics (nature.com/articles/s4158…; nature.com/articles/s4158…). @WUADRC WashU Medicine Neurology

Introducing Willow, our new state-of-the-art quantum computing chip with a breakthrough that can reduce errors exponentially as we scale up using more qubits, cracking a 30-year challenge in the field. In benchmark tests, Willow solved a standard computation in <5 mins that would

Excited to share our new paper! We mapped proteomic changes in AD models, revealing shared pathways with human AD and delayed protein turnover in amyloid plaques. Read more:nature.com/articles/s4146… Junmin Peng Yansheng Liu #proteomics #MassSpec #Proteinturnover #Alzheimers

Thrilled to share our latest work published in Cell: Turnover Atlas of Proteome and Phosphoproteome Across Mouse Tissues and Brain Regions! cell.com/cell/abstract/… Yansheng Liu Junmin Peng Eugenio F. Fornasiero Yale School of Medicine Yale Pharmacology Yale Cancer Biology Institute @HUPO #Proteomics #TeamMassSpec

Online now: Comprehensive characterization of metabolic consumption and production by the human brain dlvr.it/TJmXB9

'#Proteomic landscape of #AlzheimersDisease: emerging technologies, advances and insights (2021 – 2025)' Jay M. Yarbro, Him K. Shrestha...Junmin Peng Junmin Peng Structural Biology at St. Jude Children's Hospital @StjudeResearch …arneurodegeneration.biomedcentral.com/articles/10.11…