Genetic overlap between vascular pathologies and Alzheimer's dementia and potential causal mechanisms

A large-scale genomics resource of East Asian ancestry made available by Taiwan Biobank. A joint project with Chia-Yen Chen @DrYenFengLin Tian Ge Anne Feng Mark Daly and many others!

Excited to see this paper online. Great collaboration with Tian Ge Yunfeng Ruan🌻 #StandWithUkraine🌻 Yen-Feng Lin Chia-Yen Chen Max Lam Alicia Martin Shengying Qin and many others!

“Taiwan Biobank: A rich biomedical research database of the Taiwanese population" Anne Feng Yen-Feng Lin cell.com/cell-genomics/…

Our latest preprint: a novel cross-ancestry fine-mapping method with much improved power and calibration. A collaboration with @kaiyuan1990 Ryan Longchamps Antonio F. Pardiñas Tian Ge Chia-Yen Chen Yen-Feng Lin @bmneale Mark Daly PGC Consortium among others! medrxiv.org/content/10.110…

Hi everyone, Our paper about boosting the power of GWAS using polygenic scores (PGS) is just out in Nature Genetics. Please check it out here: nature.com/articles/s4158…

Analysis across Taiwan Biobank, Biobank Japan, and UK Biobank identifies hundreds of novel loci for 36 quantitative traits dlvr.it/SywCCn

Thrilled to announce our latest study published in Cell Genomics ! cell.com/cell-genomics/… Big shoutout to our amazing collaborators Chia-Yen Chen Tian Ge Hailiang Huang Anne Feng and many others! #GWAS #TaiwanBiobank🧬

Taiwan Biobank: A rich biomedical research database of the Taiwanese population Top cited paper from Cell Genomics - 17 citations hubs.ly/Q02m-NVf0 Anne Feng Yen-Feng Lin

Do you calculate #polygenic scores? Is it tedious and time-consuming? Try GenoPred! Easily installed, reproducible analysis, single command line. Choice of analysis methods, diverse ancestries.

Introducing real-time PRS-CS! Excited to share our new preprint with Tian Ge. Optimized for healthcare settings, rtPRS-CS ensures patients receive the most up-to-date genetic risk prediction by dynamically updating PRS weights using streaming data. 1/7 medrxiv.org/content/10.110…

Excited to share that our new paper in Nature Genetics! Huge thanks to Hailiang Huang and Tian Ge for supervising this project and to Broad Institute, CGM at MGH and PGC Consortium for supporting the research. rdcu.be/dR0sF

Excited to share our paper on the methodology of MR‐based causal mediation analysis in Statistics in Medicine! Many thanks to Shu-Chin Lin, Chia-Yen Chen, Tian Ge, and ShengHsuan Lin. bit.ly/4aWycFI #MendelianRandomization #MediationAnalysis