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Thrilled to share our new work on local genetic correlation🍾. We introduce a new method SUPERGNOVA (with a silent 'g') that is robust to local LD and arbitrary GWAS sample overlap. Wonderful collaboration with @YiliangTracy & Hongyu Zhao at Yale biorxiv.org/content/10.110…

Our genetic correlation benchmark paper with @YiliangTracy Hongyu Zhao is published today @BriefingBioinfo academic.oup.com/bib/advance-ar…

Happy to share the work led by Wei, Wenxuan, Ming with contributions from Zihan, Biqing, Zhaolong, Daiwei and collaborators Naftali, Michael, Louise, and Maor to infer cell types whose genetically regulated proportions are associated with disease. medrxiv.org/content/10.110…

Thrilled that our paper with Hanmin & Lin from Tsinghua University and James Li at UW is finally published Nature Communications today🍾🍾🍾 We introduce a scan statistic approach to identify specific genomic regions showing correlated effects on multiple traits. nature.com/articles/s4146…

While you are here, check out our related preprint on local genetic correlation estimation with @YiliangTracy and Hongyu Zhao. We also have exciting work on multi-trait modeling for de novo variants. We are hoping to get it preprinted soon so stay tuned! biorxiv.org/content/10.110…