🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Interested in 3D epigenomics? Join this #hackathon organized by 4DNucleome students and postdocs, w/ projects from the groups of William Stafford Noble, Yun Li, Dariusz Plewczynski, Yin Shen, LomvardasLab, Geoff Fudenberg, Christina Leslie, Katie Pollard, and me. March 18-21, 2024 in Seattle University of Washington

nature.com/articles/s4158… I am very excited to share our recent paper on nature . It is a great collaboration with Dr. Murre and Dr. Fisch at UCSD. We discovered a molecular mechanism to shape nuclear morphology. Cleveland Clinic Lerner Research Institute

Excited to share "Multiplexed Effector Guide Arrays" (MEGA) tech, led by Victor Tieu Victor Tieu & collaboration with Dr. Crystal Mackall, in Cell Cell. A leap in T cell transcriptome & metabolic engineering for cancer therapy. Congrats to team! authors.elsevier.com/a/1ie1VL7PXqPm4

PRC2 is reported to bind RNA. Yet, genetic experiments have raised serious questions about their functional relevance. Our paper revisits the biochemical evidence supporting widespread PRC2-RNA interactions and finds that many of these do not occur in vivo.

Thrilled to announce our latest work in Cell! We've developed a new human neuron model that effectively mimics tau aggregate spread in tauopathy. Details here: cell.com/cell/fulltext/… (1/5)

How to pick a problem. Today in Cell. 1/53 cell.com/cell/fulltext/…

📢'The World Is Your Oyster' is for those who are born in global north countries--don't experience visa bureaucracy & emotional burden that non-white global south scholars do. Citizenship is a privilege that we need to recognize in the academe. 1/n nature.com/articles/d4158…

I just ran across this and I love the author's reasoning for not using Bonferroni correction as much as we do in science. ncbi.nlm.nih.gov/pmc/articles/P…

Join us for our annual Genotech Symposium taking place 9/9/24 in the UCSF Mission Bay campus. The goal of the symposium is to foster interactions between industry & academia. We have an amazing lineup of speakers & registration is free of charge! genotech.ucsf.edu/home

Four last days to register! Symposium on 9/9. We have a great lineup of speakers, plenty of time to network and registration is free. genotech.ucsf.edu/home

New ENCODE Project preprint from the lab! Through CRISPR screens, we identify functional enhancers for neuropsychiatric disease risk genes in iPSC-derived neurons. We revealed an exciting allelic compensation effect (ACE) on transcription for the dosage-sensitive gene SIN3A.

Join us on Nov 18 at UC San Francisco for the QBI Chromatin Symposium, led by Drs. Vijay Ramani & Yin Shen. This event will showcase the latest in chromatin regulation, from bench to bedside. We look forward to seeing you there next week! Register now: qbi.ucsf.edu/qbi-chromatin-…

It was both inspiring and enriching to have this remarkable and synergistic group come together for the QBI Chromatin Symposium today!

In collaboration with Reuben Saunders, Jonathan Weissman's Lab, and Xiaowei Zhuang, we are very excited to release Perturb-Multi: a platform for pooled multimodal genetic screens in intact mammalian tissue. Check it out! biorxiv.org/content/10.110…

🌟 SAVE THE DATE! 🌟 The 4th Neuroepigenetics & Neuroepitranscriptomics Conference is returning with its 4th edition! 🎉 Join us for this incredible event, chaired by Hongjun Song (University of Pennsylvania) and Li-Huei Tsai (MIT), in beautiful sunny St Julians, Malta! ☀️ 💥

Join us for GRC/GRS: Genome Architecture in Cell Fate and Disease this June in Ventura, CA!

Our latest research on human accelerated regions has just been published with Springer Nature rdcu.be/ebo7a. Congratulations to Xiekui Cui Han Yang and the team! In this study, we characterize genome variants to function through the lens of evolution.

How did we evolve brains capable of learning and complex language? Institute for Human Genetics at UCSF found that parts of our DNA evolved at hyperspeed, making our brains more complex than apes’, but possibly raising the risk of human brain disorders. tiny.ucsf.edu/ZySms3

Excited to see our work on HARs highlighted by Trends in Genetics—appreciate the feature!

🚨 Don’t forget to register for #Neuroepi25! ⏳ The deadline is fast approaching - Thursday 7th August 2025. This is your last chance to join; don't miss out on a fantastic meeting! Click here to register➡️ bit.ly/45dN5Ck #FusionNeuro #FusionAgingResearch