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Results of Target: Stroke Phase II ⬇️⬇️DTN times ⤴️⤴️ Clinical Outcomes Stroke AHA/ASA AHA Research American_Stroke Achieving More Rapid DTN Times and Improved Outcomes in Acute Ischemic Stroke in a Nationwide Quality Improvement Intervention ahajournals.org/doi/10.1161/ST…

Congratulations to the GWTG-Stroke/Target: Stroke Phase I and II clinical teams and hospitals on this remarkable success in improving care/outcomes for acute ischemic stroke Dr. Lee Schwamm Eric D. Peterson Dr. Deepak L. Bhatt CDC Division for Heart Disease & Stroke Prevention nancyatheart @jesse8850 Stroke AHA/ASA

Use of thrombolytics in eligible acute ischemic stroke patients with the arrive by 3.5 hours, treat by 4.5 hour metric Pre-TS: 26.5% TS Phase I: 65.5% TS Phase II: 78.7%

DTN within 60 mins in stroke guidelines and PSC criteria Yet among 25,504 ischemic stroke patients treated with tPA 2003-2009, DTN time was ≤60 minutes in only 6790 (26.6%) Timeliness of Tissue-Type Plasminogen Activator Therapy in Acute Ischemic Stroke ahajournals.org/doi/10.1161/CI…

We designed the Target: Stroke program to address these delays in care Set national goal DTN within 60 mins in 50% of eligible AIS patients 10 key best practices Performance feedback, education network American Heart Association recognition via Honor Roll doi.org/10.1161/stroke…

Target: Stroke Phase I achieved improved timeliness of tPA administration following AIS on a national scale, with lower in-hospital mortality and intracranial hemorrhage, along with an increase in the percentage of patients discharged home. doi.org/10.1001/jama.2…

Target: Phase II set the more ambitious goal of DTN within 60 min in 75% and DTN within 45 min in 50%. 🎯 achieved 🧠 outcomes improved doi.org/10.1161/stroke…

GWTG-Stroke NIH funded research. PI Ying Xian AHA Research #CardioTwitter Eric D. Peterson American_Stroke Mitchell Elkind Duke Clinical Research Institute #stroke

Ying Xian

Study found recent use of NOACs was not significantly associated with increased risk of intracranial hemorrhage among patients with acute ischemic stroke treated with alteplase. ja.ma/3BeleSb

New study provides evidence for safely using alteplase treatment in AIS patients with recent NOAC use. GWTG-STROKE data found no increased risk for bleeding complications in these patients. Ying Xian #GWTGResearch spr.ly/6014Ku4qm

I just showed my support for UNICEF and the children. Check out UNICEF USA to learn what they are doing, and how you can help too. unicefusa.org/stories/unicef…

after the release of the class I, level of evidence A recommendation, 53.0% of patients with minor ischemic strokes did not receive DAPT Dual Antiplatelet Therapy in Patients With Acute Ischemic Stroke ja.ma/3iH5pL9 via JAMA Internal Medicine part of JAMA Network Dr. Deepak L. Bhatt

Learn to use the AHA Precision Medicine Platform (ow.ly/Z4oG50NAx0b) to conduct your own GWTG-Stroke analyses! Amazing opportunities & mentorship, especially for early career investigators, with leaders like Gregg Fonarow MD Dr. Deepak L. Bhatt Ying Xian . WOW. ow.ly/fcbK50NAx0e

Latest American Heart Association GWTG-Stroke research Ying Xian Eric D. Peterson Duke Clinical Research Institute Dr. Lee Schwamm AHA Research AHA Science American_Stroke CDC Division for Heart Disease & Stroke Prevention JAMA

Vitamin K Antagonist Use and Intracranial Hemorrhage After Endovascular Thrombectomy jamanetwork.com/journals/jama/… #cardiotwitter #cardiology #stroke #neurology JAMA AHA Science AHA in New York City

Can a traditional Chinese medicine improve CV outcomes post AMI? Read the surprising results in JAMA online today jamanetwork.com/journals/jama/…