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Class II HLA explains up to 10% variance of antibody responses in African infant cohorts for pertussis, diphtheria and hep B vaccines! nature.com/articles/s4159…

Financial incentives works for Singaporeans, grad students, and obese teenagers 🤗

WFH in Nature! In an RCT, hybrid WFH improved retention without damaging performance. Perceptions about WFH improved after experimentation. The power of a well conducted experiment! 😎 nature.com/articles/s4158…

RSV vaccines highly effective against hospitalisation and ED encounters for older adults. Hopefully coming to children soon! thelancet.com/journals/lance…

‘Safety signal’ in Moderna’s RSV vaccine studies halts trials of other vaccines for childhood killer | Science | AAAS science.org/content/articl…

Our data shows that immunocompromised children need SARS-CoV-2 boosters every 6-12 monthly frontiersin.org/journals/immun…

Vaccine-induced T cell responses control Orthoflavivirus challenge infection without neutralizing antibodies in humans | Nature Microbiology ⁦Shirin Kalimuddin⁩ ⁦Antonio Bertoletti⁩ Bertoletti Lab⁩ ⁦Kuan Rong Chan⁩ nature.com/articles/s4156…

Senescent T cells and CMV associated T cells associated with arterial stiffness and cardiovascular disease! nature.com/articles/cmi20…

Both SARS-CoV2 vaccination and infection do not results in long lived plasma cells in the bone marrow 🤯 very strange! nature.com/articles/s4159…

Consider “transcriptotype” to bridge the gap between genotype and phenotype, as cells can randomly and stably commit to gene expression from a single allele. This explains some of the incomplete penetrance in inborn errors of immunity nature.com/articles/s4158…

Get ready to submit your case reports and research papers in the new Journal of Human Immunity! Meet the amazing group of Editors who will be leading the Journal 👉 bit.ly/3EZ0Rhs

Can mucosal immunity ever be durable? Or is durable immunity to viral disease only ever limited to viruses with obligate viremic spread? journals.plos.org/plospathogens/…

8.6% of children worldwide have a lower respiratory tract infection associated with RSV before 24 months of age academic.oup.com/jid/article/22…

RSV reinfection rate decreases by 70% for (only) the first 6 months after an infection academic.oup.com/aje/article/17…

Cancer patients with B cell malignancies and differential expression of CD24, CDK14 and PLEKHG1 have highest risk of breakthrough infections after SARS-CoV2 vaccination nature.com/articles/s4154… Thank you Kuan Rong Chan Raghav Sundar for the collaboration! 😎

Lower respiratory tract infections until 18m of age with Nirsevimab - driven mainly by reduction in RSV and parainfluenza 1-4 but not hMPV. No signal of replacement with non-RSV respiratory viruses. academic.oup.com/cid/article/do…