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New breakthrough in lipidomic analyses just dropped in ACS Analytical Chemistry Journals today🥳We developed an innovative strategy for sn-position-resolved quantification of aminophospholipids using iDileu and IM-MS🎉Huge congrats to Shuling, Zhijun(Andrew) Zhu and all co-authors👏 pubs.acs.org/doi/full/10.10…

AAAS in Boston in February. Hint- the exposome is part of what is next. aaas.confex.com/aaas/2025/meet…

Fantastic multiomics research by Yike Shen |沈忆珂 and her team, exploring metals, the microbiome, and early-life health. Thrilled to be involved—check it out ✅

🚨 Postdoc Opportunity in Chemical Exposomics at Department of Environmental Science at Sthlm Uni. Join INQUIRE_EU project to improve indoor air quality. 🌍 Based at SciLifeLab, with guidance from Prof. Jon Martin and Dr. Stefano Papazian in a dynamic research team. 📝 Apply now in su.se/english/about-….

Great work by Yunjia Lai and Souvarish Sarkar They made the cover of Science Signaling. Biotin mitigates manganese-induced toxicity |science.org/doi/10.1126/sc…

The new issue of #ScienceSignaling has arrived! The B vitamin biotin can shield neurons from Parkinson’s-like symptoms triggered by manganese toxicity, scientists delineate how diverse viruses block a cellular antiviral pathway to replicate, and more. scim.ag/40id9ss

Our nature protocol on accessible high-sensitivity #PASEF #proteomics is featured on Nature homepage this week! Follow our workflow to reach 7k proteins & 29k phosphosites in 21min using dia-PASEF, synchro-PASEF & py_diAID. nature.com/nprot/ @PatiSkowronek #TeamMassSpec

Thrilled to share our paper on the role of biotin in Metal-Induced Parkinson’s Disease is the cover article of Science Signaling (Jan 21, 2025)! 🚀 This research opens new avenues for Parkinson's treatments. Gary W Miller Yunjia Lai Read it here: science.org/doi/10.1126/sc…

Manganese toxicity damages neurons and mitochondria by disrupting #biotin metabolism, but can be reversed with supplements of biotin to prevent #neurodegeneration and #Parkinsons-like symptoms, shows new research in fruit flies. Yunjia Lai ColumbiaPublicHealth scim.ag/40GvkJE

Scientists have tracked microplastics moving through the bodies of mice in real time The tiny plastic particles are gobbled up by immune cells and eventually become lodged in blood vessels in the brain go.nature.com/40KQciU

DeepSeek-R1 is great, but it still does not handle genomics yet :) 🚀 We’re thrilled to announce that IntegrAO (pronounced "integral") 🧬🔬—our new multi-omics integration framework—has been published in Nature Machine Intelligence! 📑 Paper: nature.com/articles/s4225… 💻 Code:

Insight from the Mayo Clinic on the environment and health newsnetwork.mayoclinic.org/discussion/may…

The largest medical #AI randomized controlled trial yet performed, enrolling >100,000 women undergoing mammography screening, was published today The Lancet Digital Health The use of A.I. led to 29% higher detection of cancer, no increase of false positives, and reduced workload compared

Interesting survey commented out in nature shows that researchers believe AI outperforms humans in 20+ research tasks. Sebastian Porsdam Mann University of Copenhagen notes: 'What really stands out is the imminence of this.' Research is just beginning to adapt. nature.com/articles/d4158…

Best exposome paper to date? It has my vote. UK Biobank...exposome > genome for all-cause mortality. nature.com/articles/s4159…

Our lifestyle and environmental exposures are the predominant influencers of healthy aging and premature mortality, compared with polygenic risk, in the first comprehensive assessment nature.com/articles/s4159… Nature Medicine

A novel #MachineLearning framework—Mal-ID—can decipher an individual’s immune system’s record of past infections and diseases, according to a new Science study, providing a powerful tool with the potential for diagnosing autoimmune disorders, viral infections, and vaccine

Exciting paper in Nature Methods that pushes the boundaries of MSI and spatially-resolved omics🥳TEMI reaches single-cell spatial resolution and enables the profiling of hundreds of lipids, metabolites, peptides, and N-glycans in complex tissue. Check out: rdcu.be/eiIWy

Happy to see this commentary appear 20 years on from proposing the #exposome to complement the #genome. The goal was to encourage fresh approaches in studying environmental/ non-genetic causes of disease as a path to #prevention. ISEE Env Epi Cancer Prevention Research academic.oup.com/exposome/artic…

New Science Magazine Exposomics. We're not doing nearly enough to understand and mitigate our toxic environmental exposures. A very insightful perspective science.org/doi/10.1126/sc…