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We exemplify the importance of curvature-responsive mechanical regulation of epithelial cells for self-organized tissue morphogenesis by using developing murine lungs.

Mechanical forces in organoids is the cover story of Nature Cell Biology. Back to back papers by Prisca Liberali Edouard Hannezo and our lab! Cover image crafted by Gerardo Ceada Carlos Pérez-González and Qiutan Yang 😀🎈 IBEC ICREA Community

Day 7, #NationalMothWeek. Moth of the day is a tiger moth that "floats" its pupa in air and creates a golden silk basket around itself to protect against predators. Fascinating defense behavior! Photo: J. Horstman. #moth_week National Moth Week

PhD scholarship alert! 📢 Mechanobiology Institute, Singapore Mechanobiology Institute, offers 11 fully-funded PhD scholarships for the August 2022 intake. Apply by 15 January 2022! For more detail, visit mbi.nus.edu.sg/education/grad…

10 days left to apply for 11 fully-funded PhD scholarships at Mechanobiology Institute (Mechanobiology Institute), National University of Singapore.

#Hiring new faculty at all levels! Seeking #PI candidates dedicated to multidisciplinary research on development, aging and repair. Successful ones will hold a joint-appointment as a Prof. / Assoc. Prof. / Asst. Prof. at a suitable department NUS. 📧 [email protected]

My lab is recruiting! We study the mechanics of epithelial deformation from cellular to embryo scales in the Drosophila embryo with (opto)genetics, imaging and theory. MTs, viscosity, nucleus, tissue conflict and more. Please RT. DM to find out more.

New review on Mechanochemical feedback loops in contact-based fate patterning! doi.org/10.1016/j.cois…

✨Geometry is everywhere!✨ Turns out cells like #curvature almost as much as I do! I'm happy to finally be able to share our work on combining 3D printing, imaging, and some math to study geometry-guided cell patterning in complex curved landscapes. nature.com/articles/s4146…

Now out online in Development doi.org/10.1242/dev.20…, we address what might make supracellular actomyosin cables that are widespread during morphogenesis different from other actomyosin: are there different components? what could a general role be? MRC-LMB Cell Biology

🚨 New Conference Alert! 🚨 MBI is organizing the "MBI Conference 2023: Mechanobiology in Health and Disease" from 26-29 Sep 2023 in Singapore 🇸🇬 Register by 15 May for early bird rates + Send in your abstract to showcase your work! Visit ↗️ mbi.nus.edu.sg/mbiconf2023

Active Deformable Cells Undergo Cell Shape Transition Associated with Percolation of Topological Defects arxiv.org/abs/2303.03580

1/9 I'm excited to share our new manuscript "Mechanical Stability of Adhesion G Protein-Coupled Receptor GAIN Domains: Insights into Mechanical Activation Hypotheses." This is our first work on adhesion GPCRs in collaboration with Dr. Gaojie Song & Dr. Tobias Langenhan. #MBIsg

We are happy to share our new bioR𝜒iv pre-print – a multidisciplinary imaging and computational approach to understanding collective cell migration in the early mouse embryo #scPhenomics #flocking biorxiv.org/cgi/content/sh…

Check out our new paper from first author and recent PhD graduate Laura Bocanegra-M. See how interkinetic nuclear movements give rise to tissue fluidisation in an epithelium. nature.com/articles/s4156… (1/n)

1/ At long last! Online Nature Cell Biology - Each day, adult barrier epithelia confront sisyphean task: How to integrate new stem cell progeny without compromising barrier integrity? We uncover their clever solution here: rdcu.be/c8Msm A tl;dr 🧵