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Asymmetric Carbohydroxylation of Alkenes Using #Photoenzymatic Catalysis by Yao Ouyang, Joshua Turek-Herman, Tianzhang Qiao, and Todd K. Hyster @HysterLab at CornellChemistry Princeton Chemistry in J. Am. Chem. Soc. pubs.acs.org/doi/10.1021/ja…

Huge congrats to our postdoc Dr. Sajjad and 3rd-year Cristina for their article on B-12 ATRP!! We’re very glad Sajjad has left his copper-based ATRP days behind him in favor of the superior metal! (Matyjaszewski Lab this is a joke) J. Am. Chem. Soc. Princeton Chemistry pubs.acs.org/doi/10.1021/ja…

KFB Lab Alert: Our latest report on decarboxylative halogenation of 3-carboxyindoles enabled by vanadium haloperoxidases is now available ChemRxiv! Halogenation generality for the win! chemrxiv.org/engage/chemrxi… Congratulations to Lauren Harstad for leading the way for this one!

What is the most important thing Erin Stache has learned from her students? Stache Lab, Princeton Chemistry Find out on her #IntroducingAngewandte page x.com/16467437/statu… onlinelibrary.wiley.com/doi/10.1002/an…

Through enzyme mining and engineering, we optimized a biocatalytic platform for enantioselective alkyl transfer: nature.com/articles/s4146… We accomplished total turnover numbers (TTN) of 1000-7000 for SAM-dependent enzymes:

Check out our most recent work in Science Magazine! We unlock new reactivity of several fluorinated gases for drug discovery, enabled by metal-organic frameworks! #MOFganicChem doi.org/10.1126/scienc…

Thanks to the efforts of our group members. This new work provides a new role of micropolarity in condensates.

Our first peer-reviewed work at University of Chinese Academy of Sciences (UCAS) is now online Angewandte Chemie Congratulations to Lu Wang and Minxu.

Both my group and Yang's group Yang Yang have demonstrated that nonheme iron enzymes can be engineered for enantioselective C(sp3)-F bond formation via iron-mediated radical fluorine transfer. Huge congratulations to the team led by postdoc Qun Zhao Zhao Qun , now a professor

It is great to share our preprint on nonheme Fe enzyme-catalyzed fluorine atom transfer (soon to appear in Nature Synthesis): chemrxiv.org/engage/chemrxi… We evolved ACCO to catalyze C-F bond formation with stereocontrol. Great to report this together with Xiongyi Huang-JHU Biocatalysis at JHU!

KFB Lab Alert: Congratulations to Manik Sharma, Zoe Patton, Carlie Shoemaker, and John Bacsa on completing our first work on biocatalytic nitrogen-halogen (N-X) bond formation (now on ChemRxiv)! Lots more to come in this area soon! chemrxiv.org/engage/chemrxi…

Excited to share the preprint of our latest work, led by graduate students James Zhang James Zhang and Anthony Huls Anthony Huls, on engineering nonheme iron enzymes for new-to-nature transformations! We evolved hydroxymandelate synthase from Amycolatopsis orientalis (AoHMS) to

KFB Lab Alert: Congratulations to Manik Sharma, Cameron Pascoe, and Stacey K. Jones on completing our first efforts toward using enzymatic halide recycling for intermolecular heterocycle synthesis. An awesome collaboration with The Davis Lab! chemrxiv.org/engage/chemrxi…

Catalytic asymmetric dearomatization is a powerful tool to convert flat aromatic compounds into 3D scaffolds. However, catalytic asymmetric dearomatization via a radical mechanism is difficult. We provide a new biocatalytic solution: nature.com/articles/s4155…

Our work on nonheme iron enzyme-catalyzed olefin trifluoromethylative difunctionalization is now published in J. Am. Chem. Soc. ! (link: pubs.acs.org/doi/abs/10.102… Previous ChemRxiv version chemrxiv.org/engage/chemrxi…). This study was led by graduate students James Zhang & Anthony Huls , with key

KFB Lab Alert: Our first report on chemoenzymatic diazo synthesis enabled by VHPO-mediated hydrazone oxidation is now available ChemRxiv! Congratulations to Manik Sharma and Yue Li for leading this effort and The Davis Lab for another fruitful collaboration!

I am thrilled to share our recent Nature Catalysis cover-featured paper on engineering nonheme iron enzymes for metallophotoredox catalysis, enabling decarboxylative C-N₃ and C-SCN bond formation nature.com/articles/s4192…. This work was pioneered and led by graduate student Jinyan

Join us! We are looking for a new team member (PhD student) with strong background in organic chemistry. 🙏 RETWEET (We want to recruit internationally) Organic chemistry meets #DirectedEvolution Highly interdisciplinary & passionate research group uni-bielefeld.hr4you.org/job/view/4339/…