Clear cell metaplasia in a sigmoid polyp from my colleague Amy Leeming. Resembles secretory endometrium and perhaps Sertoli cells! No clinical importance but pretty! Nice review by Dabir, van der Post & Nagtegaal. Histopathology, 2021. 78: 348-357 #GIpath #Pathologists Pathkids.com

Join us at our Annual Research Symposium that will be held on the 24th of Sept. An opportunity to showcase your work and achievements to your peers, colleagues, and learn from the experts in the field. Be part of this scientific (a little geeky 🤓) event and submit your abstract

1/2 📊 Study of liver biopsies in systemic mastocytosis: 🔬 High mast cell infiltration linked to ↑ alkaline phosphatase 🧬 CD30+ mast cells more common with high infiltration ❇️ Fibrosis severity associated with portal hypertension 🔓 bit.ly/3W20jOb #livertwitter

و أخيرا، فتحنا التسجيل لمخيمنا الصيفي للسنة الثانية على التوالي. لكن هالمرة أكبر و أقوى، بالتعاون مع فريق قسم الأبحاث والابتكار من جامعة الملك فهد للبترول والمعادن. نستناكم، ومعنا مشرفين من #جاها و #kfupm عشان نطلع معكم بمقترح بحثي جاهز للتقديم 🤩 #مخيم_جاها_البحثي #JASRBC_2024

#openaccess #gipath Tumour deposits are associated with worse survival than extranodal extension; a network meta‐analysis on tumour nodules in colorectal cancer - Brouwer - Histopathology - Wiley Online Library onlinelibrary.wiley.com/doi/full/10.11…

Two new studies on mutated blood stem cells clones, appearing frequently in our blood with aging (known as CHIP) —strong association with atherosclerosis nature.com/articles/s4159… —benefit of colchicine, an anti-inflammatory agent, vs atherosclerosis in mice and heart attack in

Noteworthy progress in cancer treatment. Not long ago, KRAS, one of the most important driver mutations, was considered undruggable (i.e. no Rx). Now there are 2 drugs approved and this discovery of a single molecule that inactivates 13 of 17 of KRAS's most common mutations

Hepatic Amyloidosis ~ H&E, Trichrome, PAS, and Congo Red stains ~ #LiverPath #Pathology #Hepatology

Colorectal adenosquamous carcinoma: clinicopathologic analysis of two large cohorts and literature review confirm poor prognosis and reveal prognostic aspects - Gonzalez - Histopathology - Wiley Online Library #GIpath Raul S. Gonzalez, MD onlinelibrary.wiley.com/doi/full/10.11…

Stomach Glandular Siderosis (Pattern C deposition) Iron confined to glandular epithelium, no stromal involvement or reactive changes. 🩸 Associated with systemic iron overload, chronic transfusions, or hematologic disorders. Rare, often asymptomatic. #Pathology #GIPath #IronStain

Chronic Budd-Chiari Syndrome - Midzonal congestion, hemorrhage, and necrosis, hepatocyte atrophy, congested sinusoids, and intact periportal hepatocytes - Zone 3 dropout, fibrosis, ductular proliferation, and cirrhosis Trichrome: Perisinusoidal fibrosis #Pathology #LiverPath

"Biopsy of duodenum with amyloid deposits (Congo red-positive), No apple-green shot, but mass spectrometry confirms serum amyloid A-type marking the first clue to systemic AA amyloidosis. GI amyloidosis often signal systemic disease. 10.1056/NEJMoa070265 #GIPathology

GEP‐NETs are the 2nd most prevalent neoplasm of gastrointestinal origin after #ColorectalCancer. AJCC outlines their version 9 updates, including advocating against the use of serum chromogranin A for the diagnosis &; monitoring of GEP‐NETs. Read at: acsjournals.onlinelibrary.wiley.com/doi/full/10.33…

Liver mass Nodular Elastosis/Segmental Atrophy of the Liver - Nodular regions of parenchymal atrophy with collapsed/no hepatocytes - Prominent elastic fibers - Minimal inflammation Unclear pathogenesis, possibly linked to chronic ischemia/vascular injury #LiverPath

Struggle with “ballooned” hepatocytes? Dr. Allende has some useful tips! Hans Popper Hepatopathology Society USCAP #USCAP2025

Failed Graft due to Hepatic Artery Thrombosis - Coagulative necrosis of liver parenchyma, sparing portal tracts (picture 1) - Ischemic cholangiopathy: large duct mucosal ulceration, bile extravasation (2) & perivenular cholestasis (3 & 4) #LiverPath #PathTwitter

The new ACG 2025 guideline on gastric premalignant conditions highlights what really matters in our reports #GIPath ACG Clinical Guideline: Diagnosis and Management of Gastric ... : Official journal of the American College of Gastroenterology | ACG journals.lww.com/ajg/abstract/2…

New in #HumPathol: Chimeric Antigen Receptor (CAR) T-Cell Therapy-Related Gastrointestinal Toxicity: Histologic Features and Morphologic Mimics. sciencedirect.com/science/articl… #pathology #PathTwitter #PathX #GIpath

🇸🇦 Join us at the Saudi Liver Meeting (SLM) — the premier hepatology gathering in Riyadh! 🗓️ 16–18 October 2025 📍 VOCO Hotel, Riyadh 🎓 29 CME Hours Accredited 🔗 Register now: saslt.vax.solutions #SLM2025 #SASLT #LiverCare #Hepatology #CME